Public data mining shows extended linkage disequilibrium around ADAM33
Allergy 62 (4), 444–446.
doi:10.1111/j.1398-9995.2006.01298.x
The Allergy website seems to omit the online supplement. Please find the figures here.
If you wish to draw your own figure, download haploview 4 and import the data for Figure 1, Figure 2 and Figure 3 A|B
Figure 1
Pairwise linkage disequilibrium on a 270 kbp region on chr20 (3,430,000..3,700,000 bp) in CEU (European Hapmap) individuals. Note ADAM33 SNPs showing both upstream and downstream LD.
white color: LOD < 2 and D’ < 1
blue: LOD < 2 and D’ = 1
shades of pink/red: LOD ≥ 2 and D’ < 1
bright red: LOD ≥ 2 and D’ = 1
click to zoom in
Figure 2
Pairwise linkage disequilibrium on a 270 kbp region on chr20 (3,430,000..3,700,000 bp) in CEU (European Hapmap) individuals in the Perlegen data set. Note the gap around ADAM33.
Figure 3
Pairwise linkage disequilibrium on a 260 kbp region on chr20:3,390,000..3,650,000 in European Hapmap individuals tested with Affymetrix 500 K SNP chips. Note the low resolution at ADAM33. SNP rs598418 shows LD to SNPs in ATRN and SN.
Addendum
NIEHS has resequenced ADAM33