But let your communication be Yea, yea; Nay, nay: for whatsoever is more than these cometh of evil

Mirror neurons and science careers

Spiegel online has an excellent report about mirror neurons, empathy, social background and research (taking up a theme in the ZEIT 2003)

“In unserer Kultur sind am erfolgreichsten die”, sagt Gruen, “die am meisten von ihren Gefühlen, von der Fähigkeit zum Mitgefühl abgeschnitten sind.”

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Sunday, April 26th

Shift happens

The current issue of the blue journal has more stuff on the vitamin D hypothesis (that has been shifted recently into the opposite direction). I agree with the editorial that

Intervention studies of vitamin D in the primary prevention and treatment of asthma raise a number of difficult scientific, ethical, and regulatory issues.

That may be true while the editorial includes the widely quoted myth that immunological effects occur only at high doses (Show me more…)

Wednesday, April 22nd

Fact or fancy

Just recently I came across a paper of David Marsh in 1992 on a major allergy gene “Fact or Fancy”. Many years later, the response is clear! Nevertheless the title remains popular at pubmed for reviews (N=42) – did they all read Asimov?

Tuesday, April 21st

Law not right

Wednesday, April 15th

Why just C11orf30?

I have already seen this data in Washington and even talked to one of the two first authors (pun!) at the airport – the first genomewide scan for atopic dermatitis is now being online at the nature genetics website. The overall effects are disppointing small – my quick plot gives the cumulative (sic!) negative log p values.

screenshot
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Tuesday, April 7th

Epistemic disruption

A new First Monday paper examines our modern publishing system that has been driving the art of doing science into a primitive strategy of making impact points.

These disruptive forces are represented by changing technological, economic, distributional, geographic, interdisciplinary and social relations to knowledge. The article goes on to examine three specific breaking points. The first breaking point is in business models — the unsustainable costs and inefficiencies of traditional commercial publishing, the rise of open access and the challenge of developing sustainable publishing models. The second potential breaking point is the credibility of the peer review system: its accountability, its textual practices, the validity of its measures and its exclusionary network effects. The third breaking point is post–publication evaluation, centered primarily around citation or impact analysis. We argue that the prevailing system of impact analysis is deeply flawed.

yea, yea.

Saturday, April 4th
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