But let your communication be Yea, yea; Nay, nay: for whatsoever is more than these cometh of evil

Why just C11orf30?

I have already seen this data in Washington and even talked to one of the two first authors (pun!) at the airport – the first genomewide scan for atopic dermatitis is now being online at the nature genetics website. The overall effects are disppointing small – my quick plot gives the cumulative (sic!) negative log p values.

screenshot
(Show me more…)

Tuesday, April 7th

Epistemic disruption

A new First Monday paper examines our modern publishing system that has been driving the art of doing science into a primitive strategy of making impact points.

These disruptive forces are represented by changing technological, economic, distributional, geographic, interdisciplinary and social relations to knowledge. The article goes on to examine three specific breaking points. The first breaking point is in business models — the unsustainable costs and inefficiencies of traditional commercial publishing, the rise of open access and the challenge of developing sustainable publishing models. The second potential breaking point is the credibility of the peer review system: its accountability, its textual practices, the validity of its measures and its exclusionary network effects. The third breaking point is post–publication evaluation, centered primarily around citation or impact analysis. We argue that the prevailing system of impact analysis is deeply flawed.

yea, yea.

Saturday, April 4th

I don’t want to bid for this dinner

NYT reports that Knome plans to offer its personal gene-sequencing service to the highest bidder in an eBay auction set to begin on Friday and continue for 10 days. This will include also a private dinner (Show me more…)

Friday, April 3rd

Did you know?

Wednesday, April 1st
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