Nature magazine has a collection of interesting opinions about future developments of science. My favorite contribution is open content management
The next big thing will come from connecting people and ideas together with a Google-like simplicity — making Wikipedia, Facebook and all sorts of other things completely seamless. It sounds obvious and yet it’s hard to imagine. But then, before Google it was hard to imagine what search could be like. Before Tim Berners-Lee it was hard to imagine the web.
The main invention that I would need is some wiki like content management for my hard-disk putting together all PDFs, PDFs, Rs, DOCs, EMLs under a coherent user interface. I already tried some layout during the last holidays but still do not have a good idea how to proceed, yea, yea.