In my recent review on vitamin D and allergy I introduced the rather new concept of epigenetic priming of the offspring’s vitamin D system. I could find only a limited number of studies supporting this view. Fortunately, there is a new study published today that gives me some support. Using a twin design the authors (AJCN. First published ahead of print May 30, 2012 as doi: 10.3945/ajcn.112.035683) find
Our results suggest that maternal circulating 25(OH)D is the most significant regulator of neonatal circulating 25(OH)D concentrations, with underlying genetic factors playing a limited role.