“what a shit-show life-sciences have (at least partially) become”

quoting another blog from my current reading list

an application specialist …  gave a day of training on qPCR applications in general and these instruments specifically. The scientist got to a point in her presentation where she was describing frequent errors and pitfalls in qPCR methods for quantitating gene expression, and she gave about 10 different examples that started out “I visited this one lab, and upon discussing their workflow with them it turned out they were making huge error such-and-such.” At this point, I raised my hand and asked for her honest estimation of how much confidence she places in qPCR or RT-PCR data that appear in standard journals. She paused for a few seconds and then tentatively admitted “maybe 25%.”