Tag Archives: Moffatt

Rare variants in GSDMA/B /IKZF3 but not in ORMDL3 are relevant for asthma

It was a heated debate (paper, blog) that was open until a most recent study that I am depicting here in more detail.

IKZF3
ORMDL3
GSDMB

Maybe there is an interaction by methylation?

The  analysis of  SNP effects is ongoing while it now looks like ORMDL3 SNPs were just hitchhikers, at least what I see.

 

Addendum 4.9.2023

Maybe there is even a vitamin interaction?