…alleviate suffering and promote the well-being of the individual. Christianity: Christian perspectives on human genome editing are diverse and complex. Some Christians might argue that the use of genome editing…
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Braun, Schickl and Dabrock try to “map the underlying ethical arguments” (p6ff in “Moral Hazard” 2018) against human genome editing. The various objections against germline genome editing can basically be…
The final statement came by email this morning statement-from-the-organising-committee-of-the-third-international-summit-on-human-genome-editing Remarkable progress has been made in somatic human genome editing, demonstrating it can cure once incurable diseases. To realise its full…
…Gerechtigkeit. Der Ethikrat geht in 68) darauf ein Natürlich würde die Freigabe von Genome Editing die Beziehung von Menschen verändern, das “vermutlich” in dem Satz lässt sich problemlos streichen. Strittig…
…gene editing. Some barcode as we used it already long ago, an artificial sequence that indicates the new insert. epigenie.com summarized the current approaches by last summer: Gestalt/Jay Shendure, barcode/Stephen…
…dem Zusammenhang die Spekulation über eine klinische Studie, die es schon aus statistischen Gründen nie geben wird? In der Editing Szene dreht sich alles um CCR5 weil sich so ein…
Wie andere verstehe nicht, warum der Ethikrat Grundsätzliches von sich geben will? Um die eigene Unsterblichkeit in der ansonsten säkularen Welt zu behaupten? Und warum suggeriert er einen Konsens, wo…
…to sequence a study sample of 100,000 monozygotic twins (only one of the pair, since their genomes are identical, and you get two phenotypes for the price of one genome…
Die Entwicklung des Gene Editing ist schwer nachvollziehbar ohne detaillierte Kenntnisse der Enzymchemie. Das neueste LJ 12/18 hat auf S.44 eine exzellente Beschreibung von BE1 (mutiertes dCas9 mit APOBEC1-Cytidin-Deaminase, Einzellstrang…
Here I describe a bug in the UCSC Genome Browser display that I found this morning. When locating a SNP on the human genome (where I have only surrounding sequence)…
…Avena sativa. Coexpression of these proteins with CRISPR–Cas9 effectors enabled light-mediated genome and epigenome editing, and revealed rapid Cas9 genome targeting in human cells. Die Optogenetik ist ein richtig grosses…
A recent email of Donna Karolchik – the maintainer of my favorite human genome viewer – reports The UCSC ENCODE browser for the human genome assembly hg18 (NCBI Build 36)…
…with the first copy number map of the human genome 3,080 million ‘letters’ of DNA in the human genome 22,205 genes, by one recent estimate 10 million single-letter changes (SNPs)…
…categories – insertions or deletions if seen from the second genome (has somebody ever thought about a minimal human genome?), mismatches and inversions. We are getting here a preview of…