{"id":10001,"date":"2018-04-26T12:01:06","date_gmt":"2018-04-26T11:01:06","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=10001"},"modified":"2018-04-26T19:01:37","modified_gmt":"2018-04-26T18:01:37","slug":"loss-of-il33-protects-against-allergy","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/04\/loss-of-il33-protects-against-allergy\/","title":{"rendered":"Loss of IL33 -\/- protects against allergy"},"content":{"rendered":"<p>A new paper in <a href=\"http:\/\/www.nature.com\/articles\/s41467-018-03911-8\">Nat Comm<\/a> shows the power of natural human gene knockouts.\u00a0Maybe the finding <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/04\/nature-genetics-corrupted-by-23andme\/\">is not really novel<\/a> but it finally proves the candidate genes &#8211; the most important asthma\/allergy paper in the last 2 years!<\/p>\n<figure id=\"attachment_10002\" aria-describedby=\"caption-attachment-10002\" style=\"width: 620px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-10002 size-medium\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-3-620x135.jpg\" alt=\"\" width=\"620\" height=\"135\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-3-620x135.jpg 620w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-3-768x167.jpg 768w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-3.jpg 1014w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><figcaption id=\"caption-attachment-10002\" class=\"wp-caption-text\">IL33, FLG, HLA-DQB1<\/figcaption><\/figure>\n<figure id=\"attachment_10006\" aria-describedby=\"caption-attachment-10006\" style=\"width: 620px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-10006 size-medium\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-4-620x104.jpg\" alt=\"\" width=\"620\" height=\"104\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-4-620x104.jpg 620w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-4-768x128.jpg 768w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/04\/screen-4.jpg 1537w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><figcaption id=\"caption-attachment-10006\" class=\"wp-caption-text\">GSDMB, BTN3A2, CCHCR1<\/figcaption><\/figure>\n<p>This is even a nice addition to the most recent review of <a href=\"http:\/\/jem.rupress.org\/content\/early\/2018\/03\/15\/jem.20172306\">primary atopic disorders<\/a>\u00a0although IL33 is only depicted there in Fig 1.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 11.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>A new paper in Nat Comm shows the power of natural human gene knockouts.\u00a0Maybe the finding is not really novel but it finally proves the candidate genes &#8211; the most important asthma\/allergy paper in the last 2 years! This is even a nice addition to the most recent review of primary atopic disorders\u00a0although IL33 is &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/04\/loss-of-il33-protects-against-allergy\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Loss of IL33 -\/- protects against allergy<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[],"class_list":["post-10001","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=10001"}],"version-history":[{"count":6,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10001\/revisions"}],"predecessor-version":[{"id":10011,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10001\/revisions\/10011"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=10001"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=10001"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=10001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}