{"id":10231,"date":"2018-05-29T16:01:16","date_gmt":"2018-05-29T15:01:16","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=10231"},"modified":"2018-05-29T16:46:52","modified_gmt":"2018-05-29T15:46:52","slug":"how-does-vitamin-d-imprinting-work","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/05\/how-does-vitamin-d-imprinting-work\/","title":{"rendered":"How does vitamin D imprinting work?"},"content":{"rendered":"<p>I have \u00a0predicted an epigenetic regulation of vitamin D <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20304056\">converting enzymes<\/a>\u00a0in 2010 to explain the programming effect of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22517291\">vitamin D supplements on later allergy<\/a>.<br \/>\nLast week, a first study examining <a href=\"https:\/\/www.liebertpub.com\/doi\/abs\/10.1089\/bfm.2017.0231?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub%3Dpubmed\">vitamin D supplement effects in newborns<\/a> has been published. They compare 400IU versus 3800IU while I am already convinced that 400 IU has some measureable effect.<\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_10232\" aria-describedby=\"caption-attachment-10232\" style=\"width: 900px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/05\/Bildschirmfoto-2018-05-29-um-16.30.20.jpg\" data-rel=\"key-image-0\" data-rl_title=\"\" data-rl_caption=\"\" title=\"\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-10232 size-full\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/05\/Bildschirmfoto-2018-05-29-um-16.30.20.jpg\" alt=\"\" width=\"900\" height=\"282\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/05\/Bildschirmfoto-2018-05-29-um-16.30.20.jpg 900w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/05\/Bildschirmfoto-2018-05-29-um-16.30.20-620x194.jpg 620w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2018\/05\/Bildschirmfoto-2018-05-29-um-16.30.20-768x241.jpg 768w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/a><figcaption id=\"caption-attachment-10232\" class=\"wp-caption-text\">table 2 screenshot of selected rows<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>So maybe I was wrong with my prediction of a differential CYP24A1 methylation, as the authors now describe CYP7B1. CYP7B1 encodes for\u00a0<b>25-hydroxycholesterol 7-alpha-hydroxylase<\/b>\u00a0which is more upstream in the\u00a0 synthesis of cholesterol.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 25.05.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>I have \u00a0predicted an epigenetic regulation of vitamin D converting enzymes\u00a0in 2010 to explain the programming effect of vitamin D supplements on later allergy. Last week, a first study examining vitamin D supplement effects in newborns has been published. They compare 400IU versus 3800IU while I am already convinced that 400 IU has some measureable &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/05\/how-does-vitamin-d-imprinting-work\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">How does vitamin D imprinting work?<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[],"class_list":["post-10231","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10231","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=10231"}],"version-history":[{"count":7,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10231\/revisions"}],"predecessor-version":[{"id":10244,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10231\/revisions\/10244"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=10231"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=10231"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=10231"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}