{"id":10580,"date":"2018-10-12T12:58:55","date_gmt":"2018-10-12T11:58:55","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=10580"},"modified":"2019-09-20T04:14:45","modified_gmt":"2019-09-20T04:14:45","slug":"purifying-selection-affect-as-much-as-95-of-the-variants","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/10\/purifying-selection-affect-as-much-as-95-of-the-variants\/","title":{"rendered":"Purifying selection affect as much as 95% of the variants"},"content":{"rendered":"<p><a href=\"https:\/\/elifesciences.org\/articles\/36317\">New research\u00a0<\/a>shows that most genetic variants in the human genome are affected by purifying selection, so there is no &#8220;neutral&#8221; variant anymore.<\/p>\n<blockquote><p>Pouyet, Aeschbacher et al. created a measure of genetic diversity that is only affected by selection or transmission bias. The results showed that negative selection influences as much as 85 percent of our genome, whereas transmission bias affects a majority of the rest of the genome. After removing these two biases, less than 5 percent of the human genome is found to evolve by chance. This suggests that while most of our genetic material is formed of non-functional sequences, the vast majority of it evolves indirectly under some type of selection.<\/p><\/blockquote>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 12.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>New research\u00a0shows that most genetic variants in the human genome are affected by purifying selection, so there is no &#8220;neutral&#8221; variant anymore. Pouyet, Aeschbacher et al. created a measure of genetic diversity that is only affected by selection or transmission bias. The results showed that negative selection influences as much as 85 percent of our &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2018\/10\/purifying-selection-affect-as-much-as-95-of-the-variants\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Purifying selection affect as much as 95% of the variants<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-10580","post","type-post","status-publish","format-standard","hentry","category-genetics-biology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10580","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=10580"}],"version-history":[{"count":3,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10580\/revisions"}],"predecessor-version":[{"id":13456,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/10580\/revisions\/13456"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=10580"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=10580"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=10580"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}