{"id":1119,"date":"2007-07-26T18:44:27","date_gmt":"2007-07-26T16:44:27","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/2007\/07\/26\/detecting-repoxygen-infection\/"},"modified":"2021-09-16T06:05:58","modified_gmt":"2021-09-16T06:05:58","slug":"detecting-repoxygen-infection","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/07\/detecting-repoxygen-infection\/","title":{"rendered":"Detecting repoxygen infection"},"content":{"rendered":"<p>Doping rules are sometimes hard to understand. Sleeping in a low pressure chamber and training at high altitudes is allowed but taking epo is not &#8211; although net effects may be the same.<\/p>\n<p>This might be a reason why some athletes are now trying to mimick more closely biology. <a href=\"http:\/\/www.oxfordbiomedica.co.uk\/news\/2002-ob-05.htm\">Repoxygen<\/a> is a viral vector known for some time that includes the human epo gene under control of a hypoxia control element. Clearly this drug has the potential to be used for doping (&#8220;<a href=\"http:\/\/www.nytimes.com\/2007\/06\/03\/sports\/playmagazine\/0603play-hot.html?ex=1338523200&amp;en=e6bfb26f7aecd04f&amp;ei=5088&amp;partner=rssnyt&amp;emc=rss\">Outlaw DNA<\/a>&#8220;). <!--more--><br \/>\nAny abuse may be immediately detected if the delivered gene sequence is not 100% identical to the human sequence (for example by resequencing the introns or looking for other remains of the viral vector9. I warn you, however, to do any experiments as infected blood cells removed from the body for a doping test will show hypoxia stress and let them produce additional epo &#8230; More seriously, read the <a href=\"http:\/\/www.sskrplaw.com\/publications\/031106.html\">Gelsinger<\/a> story.<br \/>\nToday is the day of free advice and here is my free advice: 1. An A sample is an A sample 2. Believe in what people say but not in lab results 3. They would not call it an A sample if there would not be a B sample 4. Doping is only proven with A + B sample 5. Even then may be open questions 6. do not accuse anybody without knowing the details and 7. doping is inacceptable, yea, yea.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 06.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Doping rules are sometimes hard to understand. Sleeping in a low pressure chamber and training at high altitudes is allowed but taking epo is not &#8211; although net effects may be the same. This might be a reason why some athletes are now trying to mimick more closely biology. Repoxygen is a viral vector known &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/07\/detecting-repoxygen-infection\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Detecting repoxygen infection<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1119","post","type-post","status-publish","format-standard","hentry","category-genetics-biology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=1119"}],"version-history":[{"count":1,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1119\/revisions"}],"predecessor-version":[{"id":18611,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1119\/revisions\/18611"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=1119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=1119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=1119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}