{"id":1164,"date":"2007-08-14T19:21:16","date_gmt":"2007-08-14T17:21:16","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/2007\/08\/14\/living-on-borrowed-time\/"},"modified":"2007-09-27T17:52:09","modified_gmt":"2007-09-27T15:52:09","slug":"living-on-borrowed-time","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/08\/living-on-borrowed-time\/","title":{"rendered":"Living on borrowed time"},"content":{"rendered":"

An excellent new review<\/a> summarizes our current knowledge about telomeres – the complicated chromosome end machinery that is necessary to prevent unwanted repair while allowing to track for the number of replications. Think of it like a source code control system as CVS, the Concurrent Version System<\/a>. During a recent research project on life cycle of single point mutations \/ SNPs I realized that the control of the number of cell division is a necessary limiting step as each replication introduces numerous SNPs.<\/p>\n

telomere.png<\/a><\/p>\n

\nReplicative senescence can be viewed as a mechanism to limit the potential number of population doublings a cell can undergo, hypothetically rendering it a powerful tumour-suppressor mechanism\n<\/p><\/blockquote>\n

Manipulating telomere length will therefore not lead to a longer life but to cancer. <\/p>\n

BTW the source of “borrowed time” is at phrases org.uk<\/a> – indicating time that we borrowed from death. “We may be care-worn and aged, forsaken of the world, living on borrowed time, useless so far as any activity is concerned, dependent on children, or friends; yet Jesus has loving acquaintance with us.”<\/p>\n

played again by Adam Green<\/a> in “Friends of Mine” (one of my all time favorites)<\/p>\n\n

 <\/p>\n

\n CC-BY-NC Science Surf , accessed 12.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"

An excellent new review summarizes our current knowledge about telomeres – the complicated chromosome end machinery that is necessary to prevent unwanted repair while allowing to track for the number of replications. Think of it like a source code control system as CVS, the Concurrent Version System. During a recent research project on life cycle … Continue reading Living on borrowed time<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,15],"tags":[],"class_list":["post-1164","post","type-post","status-publish","format-standard","hentry","category-genetics-biology","category-science-theology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=1164"}],"version-history":[{"count":0,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1164\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=1164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=1164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=1164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}