This was a question, I have been asked yesterday.<\/p>\n
Although dominance is the property an allele, dominance is not”regulated” on the genomic level but a function of the resulting protein. According to the largely citied Wilkie paper<\/a>\u00a0there are numerous mechanisms<\/p>\n In lay terms also explained at\u00a0biology.stackexchange<\/a><\/p>\n … the dominant allele encodes a protein that can perform its function. For example, the dominant allele for the CFTR gene encodes a channel that can let chloride into and out of the cells. The recessive allele, on the other hand encodes a protein that cannot do its job correctly (this also called a loss-of-function mutation). So if you inherit a functional copy from one parent and a non-functional copy from the other parent, you will still have one copy of the protein that can do its job. Only if you get a nonfunctional copy from both parents will you have a recessive condition called cystic fibrosis.<\/p><\/blockquote>\n\n <\/p>\n This was a question, I have been asked yesterday. Although dominance is the property an allele, dominance is not”regulated” on the genomic level but a function of the resulting protein. According to the largely citied Wilkie paper\u00a0there are numerous mechanisms reduced gene dosage\u00a0expression or protein activity increased gene dosage ectopic or temporally altered mRNA expression … Continue reading What makes an allele dominant on the molecular level?<\/span> \n