{"id":1256,"date":"2007-10-11T00:57:21","date_gmt":"2007-10-10T22:57:21","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/2007\/10\/11\/one-small-step-for-man\/"},"modified":"2007-10-13T08:06:49","modified_gmt":"2007-10-13T06:06:49","slug":"one-small-step-for-man","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/10\/one-small-step-for-man\/","title":{"rendered":"One small step for man"},"content":{"rendered":"<p>Slowly but surely, the <a href=\"https:\/\/www.wjst.de\/blog\/2007\/10\/07\/no-proof-of-hygiene-hypothesis\/\">hygiene hypothesis<\/a> is going to be more and more perforated. A new <a href=\"http:\/\/content.nejm.org\/cgi\/content\/short\/357\/15\/1487\">NEJM paper finds<\/a><!--more--><\/p>\n<blockquote><p>Hypopharyngeal samples were cultured from 321 neonates at 1 month of age. Twenty-one percent of the infants were colonized with S. pneumoniae, M. catarrhalis, H. influenzae, or a combination of these organisms; colonization with one or more of these organisms, &#8230;, was significantly associated with persistent wheeze (hazard ratio, 2.40; 95% confidence interval [CI], 1.45 to 3.99), &#8230;, and hospitalization for wheeze (hazard ratio, 3.85; 95% CI, 1.90 to 7.79).<\/p><\/blockquote>\n<p>The <a href=\"http:\/\/news.yahoo.com\/s\/hsn\/20071010\/hl_hsn\/earlybacterialinfectionmayboostasthmarisk\">editorial<\/a> writes<\/p>\n<blockquote><p>\nbacterial colonization of the [throat] in the first four weeks of life indicates a defective innate immune response very early in life, which promotes the development of asthma.\n<\/p><\/blockquote>\n<p>Accepting this view requires only a small further step <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed&#038;Cmd=ShowDetailView&#038;TermToSearch=17014620&#038;ordinalpos=3&#038;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">to the responsible environmental trigger<\/a>.<\/p>\n<p>BTW I will detail the vitamin D studies on the next meeting of the <a href=\"http:\/\/www.aaaai.org\/members\/annual_meeting\/am2008\/preliminary_program.pdf\">American Academy of Allergy, Asthma and Immunology 2008<\/a> in session # 330 &#8211; come and visit us at Sunday March 16, 2008, 10:45 in Philadelphia at the Pennsylvania Convention Center.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 26.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Slowly but surely, the hygiene hypothesis is going to be more and more perforated. A new NEJM paper finds &nbsp; CC-BY-NC Science Surf , accessed 26.04.2026<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,10],"tags":[1288,717,1287],"class_list":["post-1256","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-sunshine-vitamin","tag-alelrgy","tag-hygiene","tag-vitamin-d"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1256","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=1256"}],"version-history":[{"count":0,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1256\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=1256"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=1256"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=1256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}