{"id":14013,"date":"2019-11-01T14:31:41","date_gmt":"2019-11-01T14:31:41","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=14013"},"modified":"2019-11-01T14:33:07","modified_gmt":"2019-11-01T14:33:07","slug":"a-new-research-route-for-fighting-allergy","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2019\/11\/a-new-research-route-for-fighting-allergy\/","title":{"rendered":"A new research route for fighting allergy?"},"content":{"rendered":"<p><a href=\"https:\/\/immunology.sciencemag.org\/content\/4\/41\/eaay6125\">Sci Immunol<\/a> today shows an incomplete genetic reconstitution of B cell pools after measles infection.<\/p>\n<blockquote><p>Using B cell receptor (BCR) sequencing of human peripheral blood lymphocytes before and after MeV infection, we identified two immunological con- sequences from measles underlying immunosuppression: (i) incomplete reconstitution of the nai\u0308ve B cell pool leading to immunological immaturity and (ii) compromised immune memory to previously encountered pathogens due to depletion of previously expanded B memory clones.<\/p><\/blockquote>\n<p>This &#8220;immune amnesia&#8221; is noteworthy as sensitivity to D pter <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16854347\">was observed less frequent in children<\/a> with a history of measles than in those without.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 28.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Sci Immunol today shows an incomplete genetic reconstitution of B cell pools after measles infection. Using B cell receptor (BCR) sequencing of human peripheral blood lymphocytes before and after MeV infection, we identified two immunological con- sequences from measles underlying immunosuppression: (i) incomplete reconstitution of the nai\u0308ve B cell pool leading to immunological immaturity and &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2019\/11\/a-new-research-route-for-fighting-allergy\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">A new research route for fighting allergy?<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[],"class_list":["post-14013","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/14013","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=14013"}],"version-history":[{"count":3,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/14013\/revisions"}],"predecessor-version":[{"id":14016,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/14013\/revisions\/14016"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=14013"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=14013"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=14013"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}