{"id":1570,"date":"2008-06-02T11:59:46","date_gmt":"2008-06-02T09:59:46","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=1570"},"modified":"2008-06-02T14:08:29","modified_gmt":"2008-06-02T12:08:29","slug":"trans-border-ld","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2008\/06\/trans-border-ld\/","title":{"rendered":"Trans-border LD?"},"content":{"rendered":"<p>Occasionally I see high R^2 values even between linkage disequilibrium blocks. The following plot was obtained from the German asthma family study; basically a haploview screenshot rescaled and inverted before using the Photoshop polar filter.<!--more--><br \/>\n<a href=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2008\/06\/zwischenablage03small.png\" data-rel=\"key-image-0\" data-rl_title=\"\" data-rl_caption=\"\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2008\/06\/zwischenablage03small.png\" alt=\"\" title=\"\" width=\"480\" height=\"480\" class=\"alignnone size-full wp-image-1569\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2008\/06\/zwischenablage03small.png 480w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2008\/06\/zwischenablage03small-150x150.png 150w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/a><br \/>\n<em>this image (c) wjst.de<\/em><br \/>\nClearly at 2&#8242; 40 there is a marker that is associated also with marker on another block &#8211; there are even weak epistatic effects(p &lt; 0.05). Does this indicate any disease selection? <\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 10.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Occasionally I see high R^2 values even between linkage disequilibrium blocks. The following plot was obtained from the German asthma family study; basically a haploview screenshot rescaled and inverted before using the Photoshop polar filter. &nbsp; CC-BY-NC Science Surf , accessed 10.04.2026<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[1864,212,1735],"class_list":["post-1570","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology","tag-epistatic-effects","tag-linkage-disequilibrium","tag-marker"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=1570"}],"version-history":[{"count":0,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/1570\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=1570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=1570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=1570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}