{"id":18606,"date":"2021-09-16T06:01:26","date_gmt":"2021-09-16T06:01:26","guid":{"rendered":"https:\/\/www.wjst.de\/blog\/?p=18606"},"modified":"2021-09-17T04:52:33","modified_gmt":"2021-09-17T04:52:33","slug":"virus-reactivation","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2021\/09\/virus-reactivation\/","title":{"rendered":"Virus reactivation"},"content":{"rendered":"

A recent Nature study<\/a> showed Ebola reactivation in a previously infected patient:<\/p>\n

The 2021 lineage shows considerably lower divergence than would be expected during sustained human-to-human transmission, which suggests a persistent infection with reduced replication or a period of latency.<\/p><\/blockquote>\n

The most recent viral genome shared 10 substitutions that evolved during the previous epidemic making it unlikely that there was a new animal spillover event.\u00a0I always wondered how second & third wave of COVID-19 started in Germany. Was it really a new spread or just a reactivation? A Frontiers review<\/a> concluded from the existing literature that<\/p>\n

our study, consisting more than a total of 113,715 patients, indicates that the RP-SARS-CoV-2 scenario occurs plausibly due to reactivation, reinfection, viral shedding, or testing errors.<\/p><\/blockquote>\n

So far, there are 240 documented COVID-19 cases of reinfection reported worldwide according to the reinfection tracker<\/a>. In the case of Ebola there is a known viral persistence in semen while\u00a0 transmission through milk and cervicovaginal fluid is also possible (similar for COVID-19<\/a> although neuronal persistence<\/a> seems to be more relevant). Maybe we need more immunological studies particular in long COVID<\/a> if there is a continuous or intermittent antigenic stimulation due to persistence of an antigenic reservoir.<\/p>\n

The fourth wave in Germany is caused by the delta variant, reactivation of alpha is certainly not a major factor. So we will only know in the next few years if reactivation is responsible for small regional outbreaks in unvaccinated communities.<\/p>\n\n

 <\/p>\n

\n CC-BY-NC Science Surf , accessed 28.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"

A recent Nature study showed Ebola reactivation in a previously infected patient: The 2021 lineage shows considerably lower divergence than would be expected during sustained human-to-human transmission, which suggests a persistent infection with reduced replication or a period of latency. The most recent viral genome shared 10 substitutions that evolved during the previous epidemic making … Continue reading Virus reactivation<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[3391,3440],"class_list":["post-18606","post","type-post","status-publish","format-standard","hentry","category-genetics-biology","tag-covid-19","tag-covid19"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/18606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=18606"}],"version-history":[{"count":9,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/18606\/revisions"}],"predecessor-version":[{"id":18616,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/18606\/revisions\/18616"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=18606"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=18606"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=18606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}