{"id":2310,"date":"2009-05-13T12:25:18","date_gmt":"2009-05-13T10:25:18","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=2310"},"modified":"2009-05-13T12:35:27","modified_gmt":"2009-05-13T10:35:27","slug":"a-fancy-new-category-for-a-gwa-result-same-direction","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2009\/05\/a-fancy-new-category-for-a-gwa-result-same-direction\/","title":{"rendered":"A fancy new category for a GWA result: same direction"},"content":{"rendered":"<table>\n<tr>\n<td valign=top><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2009\/05\/screenshot7.jpeg\" alt=\"screenshot7\" title=\"screenshot7\" width=\"142\" height=\"381\" class=\"alignleft size-full wp-image-2309\" \/><\/td>\n<td valign=top>\nIsn&#8217;t that a funny new category as reported in the <a href=\"http:\/\/www.cell.com\/AJHG\/abstract\/S0002-9297(09)00148-7\">last asthma genome scan<\/a> &#8211; &#8220;same direction&#8221;? Should that provide evidence that isn&#8217;t there?<br \/>\nOf 10 samples only one replicates (FHS) and one shows borderline (COP) association to PDE4D \/ rs 1588265.<\/p>\n<blockquote><p>\n&#8230; in the absence of biological evidence we cannot exclude the possibility that the associations we measured were due to chance only\n<\/p><\/blockquote>\n<p>yea, yea.<br \/>\nBTW Also here &#8211; <a href=\"http:\/\/www.cell.com\/AJHG\/abstract\/S0002-9297(07)62723-2\">magically, previously associated genes disappear<\/a> &#8230;\n<\/td>\n<\/tr>\n<\/table>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 06.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Isn&#8217;t that a funny new category as reported in the last asthma genome scan &#8211; &#8220;same direction&#8221;? Should that provide evidence that isn&#8217;t there? Of 10 samples only one replicates (FHS) and one shows borderline (COP) association to PDE4D \/ rs 1588265. &#8230; in the absence of biological evidence we cannot exclude the possibility that &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2009\/05\/a-fancy-new-category-for-a-gwa-result-same-direction\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">A fancy new category for a GWA result: same direction<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[2453,2452,2450,2451],"class_list":["post-2310","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology","tag-chi3l1","tag-pde4d","tag-biological-evidence","tag-ormdl3"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2310","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=2310"}],"version-history":[{"count":17,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2310\/revisions"}],"predecessor-version":[{"id":2323,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2310\/revisions\/2323"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=2310"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=2310"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=2310"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}