{"id":25373,"date":"2025-07-03T12:10:47","date_gmt":"2025-07-03T10:10:47","guid":{"rendered":"https:\/\/www.wjst.de\/blog\/?p=25373"},"modified":"2025-07-18T09:40:10","modified_gmt":"2025-07-18T07:40:10","slug":"the-sudhof-nomenclature","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2025\/07\/the-sudhof-nomenclature\/","title":{"rendered":"The S\u00fcdhof Nomenclature"},"content":{"rendered":"<figure id=\"attachment_25377\" aria-describedby=\"caption-attachment-25377\" style=\"width: 354px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-03-um-11.50.48.jpg.jpeg\" rel=\"key\" data-rel=\"key-image-0\" data-rl_title=\"\" data-rl_caption=\"\" title=\"\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-25377\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-03-um-11.50.48.jpg.jpeg\" alt=\"\" width=\"354\" height=\"360\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-03-um-11.50.48.jpg.jpeg 599w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-03-um-11.50.48.jpg-492x500.jpeg 492w\" sizes=\"auto, (max-width: 354px) 100vw, 354px\" \/><\/a><figcaption id=\"caption-attachment-25377\" class=\"wp-caption-text\">Blurred as I have no image rightsSource: https:\/\/www.faz.net\/aktuell\/wissen\/medizin-nobelpreistraeger-thomas-suedhof-wie-boese-ist-wissenschaft-110567521.html<\/figcaption><\/figure>\n<p>The video can be found at the <a href=\"https:\/\/mediatheque.lindau-nobel.org\/recordings#l=38861\">Lindau Mediathek<\/a>.<\/p>\n<p>Here is my annotated list of excuses numbered as SUEDHOF1, SUEDHOF2, &#8230;,. SUEDHOF15 in chronological order.<\/p>\n<p>Is this really &#8220;an unprecedented quality initiative&#8221; as F.A.Z. <a href=\"https:\/\/www.faz.net\/aktuell\/wissen\/nobelpreistraeger-thomas-suedhof-unter-druck-von-plagiatsjaegern-19637699.html\">Joachim M\u00fcller-Jung<\/a> wrote?<\/p>\n<p>IMHO this looks more like a larmoyant defense but form your own opinion now.<!--more--><\/p>\n<hr \/>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain md-expand\">SUEDHOF1 <\/span><span class=\"md-pair-s\"><strong><span class=\"md-plain\">\u201cI&#8217;m not a chemist, so I&#8217;m not going to talk about science directly.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">This is a weak deflection. As a Nobel laureate in a scientific discipline, he carries a responsibility to engage rigorously with broader scientific issues\u2014especially those affecting public trust and integrity.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Expertise in a narrow field does not excuse disengagement from systemic issues in science.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF2 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cThe mistakes in our papers are due to digital image processing artifacts, not fraud.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Blaming technology doesn\u2019t absolve responsibility. Labs must maintain strict protocols as tools evolve. Oversight and verification should adapt accordingly.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Image-processing artifacts are a foreseeable risk, not an exoneration.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF3 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cAI software is now able to find issues nobody would have noticed otherwise.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">This advances science, not hinders it. Better detection tools are a step forward, not a reason to dismiss errors as inconsequential.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Enhanced scrutiny is progress\u2014not an excuse.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF4 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cThe accused errors don\u2019t affect the conclusions and seem absurd to fake intentionally.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Scientific integrity doesn&#8217;t rest solely on intention. Errors, even unintentional, undermine credibility and demand correction.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Absence of intent does not absolve responsibility for accuracy.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF5 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cCollaborators became collateral damage in the scrutiny, which inflates the perception of misconduct.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Widespread issues implicating multiple labs suggest systemic lapses in research oversight\u2014not just collateral fallout.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> When many collaborators are affected, the problem is likely structural.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF6 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cWe\u2019re in a new era where everything is scrutinized\u2014even by amateurs and algorithms.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Openness and scrutiny are core to science. Lamenting increased transparency suggests resistance to accountability.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Increased scrutiny is essential, not a threat.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF7 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cSome images were inserted incorrectly by mistake\u2014we couldn\u2019t tell them apart ourselves.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">If experts can\u2019t distinguish correct data, how can peer reviewers or readers trust the findings? This indicates deeper flaws in quality control.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Inability to catch errors points to insufficient internal oversight.<\/span><\/p>\n<hr \/>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF8 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cStatistical errors like pseudo-replication are common and not misconduct.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Prevalence doesn\u2019t make bad practice acceptable. Misleading statistical methods compromise conclusions, regardless of intent.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> \u201cCommon\u201d errors are still errors.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF9 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cReanalyses misunderstood our methods; our approach was acceptable in the field.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Field norms evolve, and acceptable doesn&#8217;t always mean rigorous. Transparency and willingness to adapt are crucial.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Methodological defensiveness isn\u2019t a substitute for clarity and rigor.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF10 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cScience is inherently variable\u2014different results don\u2019t mean irreproducibility.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">True, but vague variability can&#8217;t be used to brush off inconsistencies. Proper reproducibility requires controlled variation, not chaos.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Reproducibility and variability are not mutually exclusive.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF11 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cFraud exists but is rare and inevitable because science is a human activity.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Accepting fraud as inevitable risks normalizing it. Scientific systems must minimize opportunities for misconduct, not excuse it.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Human nature isn\u2019t a shield against accountability.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF12 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cMost retractions, including ours, are for minor issues\u2014not because the conclusions are wrong.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">If figures are faulty, confidence in conclusions erodes. Reproducibility depends on complete integrity of data\u2014not just overall narrative.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Faulty details undermine trustworthy conclusions.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF13 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cThe journal system pushes us to overreach.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Researchers still choose to exaggerate. Blaming journals deflects personal responsibility for claims made in published work.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Journals may incentivize overreach, but authors remain responsible.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading\"><span class=\"md-plain\">SUEDHOF14 <\/span><span class=\"md-pair-s \"><strong><span class=\"md-plain\">\u201cScience is underpaid and undervalued, especially for postdocs and professors.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Compensation issues are real\u2014but they don\u2019t excuse lapses in research standards. Integrity should be independent of salary.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Low pay doesn\u2019t justify low rigor.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-heading md-focus\"><span class=\"md-plain\">SUEDHOF15 <\/span><span class=\"md-pair-s md-expand\"><strong><span class=\"md-plain\">\u201cWe should communicate better, but public criticism (like letters or appeals) isn\u2019t useful.\u201d<\/span><\/strong><\/span><\/p>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Public critique is part of scientific discourse. Dismissing it sidelines legitimate accountability efforts.<\/span> <span class=\"md-pair-s \"><span class=\"md-plain\">Summary:<\/span><\/span><span class=\"md-plain\"> Transparency and open dialogue are essential to reform.<\/span><\/p>\n<div class=\"md-hr md-end-block\" tabindex=\"-1\">\n<hr \/>\n<\/div>\n<p class=\"md-end-block md-p\"><span class=\"md-plain\">Thomas S\u00fcdhof blends legitimate structural critiques\u2014on pay, publishing pressure, and statistical complexity\u2014with a pattern of <\/span><span class=\"md-pair-s \"><span class=\"md-plain\">defensiveness and minimization<\/span><\/span><span class=\"md-plain\">. While he correctly calls for nuanced understanding of science&#8217;s limitations, his excuses often sidestep <\/span><span class=\"md-pair-s \"><span class=\"md-plain\">direct responsibility<\/span><\/span><span class=\"md-plain\"> and risk <\/span><span class=\"md-pair-s \"><span class=\"md-plain\">undermining the very accountability<\/span><\/span><span class=\"md-plain\"> that sustains public trust in research. Strong leadership would embrace scrutiny, not diminish it.<\/span><\/p>\n<p>Ad hominem arguments &#8211; showing images of offending scientists like Elisabeth Bik and Leonid Schneider &#8211; were certainly not helpful.<\/p>\n<p><a href=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-04-um-10.59.29.jpg\" rel=\"key\" data-rel=\"key-image-1\" data-rl_title=\"\" data-rl_caption=\"\" title=\"\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-25393 size-medium\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-04-um-10.59.29-620x513.jpg\" alt=\"\" width=\"620\" height=\"513\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-04-um-10.59.29-620x513.jpg 620w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-04-um-10.59.29-605x500.jpg 605w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-04-um-10.59.29-768x635.jpg 768w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2025\/07\/Bildschirmfoto-2025-07-04-um-10.59.29.jpg 877w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><\/p>\n<p>Disclaimer &#8211; Although dispised by S\u00fcdhof, I used some LLM for video transcription, and another one for interpretation and\u00a0 language correction.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 27.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>The video can be found at the Lindau Mediathek. Here is my annotated list of excuses numbered as SUEDHOF1, SUEDHOF2, &#8230;,. SUEDHOF15 in chronological order. Is this really &#8220;an unprecedented quality initiative&#8221; as F.A.Z. Joachim M\u00fcller-Jung wrote? IMHO this looks more like a larmoyant defense but form your own opinion now. &nbsp; CC-BY-NC Science Surf &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2025\/07\/the-sudhof-nomenclature\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">The S\u00fcdhof Nomenclature<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[5062,5056],"class_list":["post-25373","post","type-post","status-publish","format-standard","hentry","category-philosophy-of-science","tag-birkenstock","tag-thomas-sudhof"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/25373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=25373"}],"version-history":[{"count":17,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/25373\/revisions"}],"predecessor-version":[{"id":25467,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/25373\/revisions\/25467"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=25373"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=25373"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=25373"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}