{"id":2591,"date":"2009-06-23T11:39:58","date_gmt":"2009-06-23T09:39:58","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=2591"},"modified":"2009-06-29T17:23:23","modified_gmt":"2009-06-29T15:23:23","slug":"neverending-story-vitamin-d-in-pregnancy","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2009\/06\/neverending-story-vitamin-d-in-pregnancy\/","title":{"rendered":"Neverending story &#8211; vitamin D in pregnancy"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2009\/06\/screenshot11-150x150.jpg\" alt=\"screenshot1\" title=\"screenshot1\" width=\"150\" height=\"150\" class=\"aligncenter size-thumbnail wp-image-2595\" style=\"display:inline;float:left;margin-right:20px\"\/>A new study of 5 year old children relates their current allergy symptoms to LOW maternal intake of vitamin D from food (which is strange within the context of current cohort studies that show a INCREASED risk by vitamin D supplement use).<\/p>\n<p>As this is a diabetes study, the sample is highly biased<!--more--> (a 15%  subset of the population is HLA-DQB1 02\/0302 heterozygous and DQB1 0302\/x positive). 7% of the original selected individuals participate in a follow up while another 1-2% are lost there due to insufficient data. So is this sample representative to allow any conclusion?<\/p>\n<p>Second, the authors find effects with dietary vitamin D which is usually less than 10% of the overall source. So is this study really about vitamin D? As the authors do not find any direct effect by vitamin D supplements, this study may be <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17980419?ordinalpos=10&#038;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">just about fish eating<\/a> which increases 3,4fold between &#8220;vitamin D exposure&#8221; groups (together with other factors like socioeconomic status).<\/p>\n<p>Third, there is no information about vitamin D supplementation in the newborn period &#8211; the most relevant question at the moment. The authors omit this from the analysis (and even from the discussion which disqualifies the paper).<\/p>\n<blockquote><p> &#8230; We lack knowledge on the mechanisms by which vitamin D [works].<\/p><\/blockquote>\n<p>I agree, this is another example, how dangerous it is to misuse studies for unintended outcomes and to reason from insufficient data. BTW Why are there only three <strong>quartile<\/strong> groups in the figure?<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 07.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>A new study of 5 year old children relates their current allergy symptoms to LOW maternal intake of vitamin D from food (which is strange within the context of current cohort studies that show a INCREASED risk by vitamin D supplement use). As this is a diabetes study, the sample is highly biased &nbsp; CC-BY-NC &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2009\/06\/neverending-story-vitamin-d-in-pregnancy\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Neverending story &#8211; vitamin D in pregnancy<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,10],"tags":[1287],"class_list":["post-2591","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-sunshine-vitamin","tag-vitamin-d"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=2591"}],"version-history":[{"count":14,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2591\/revisions"}],"predecessor-version":[{"id":2676,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2591\/revisions\/2676"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=2591"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=2591"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=2591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}