{"id":2977,"date":"2009-12-29T20:29:19","date_gmt":"2009-12-29T18:29:19","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=2977"},"modified":"2010-01-06T21:10:35","modified_gmt":"2010-01-06T19:10:35","slug":"lamarck-and-fixation-of-epigenetic-marks-as-mutations","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2009\/12\/lamarck-and-fixation-of-epigenetic-marks-as-mutations\/","title":{"rendered":"Lamarck and fixation of epigenetic marks"},"content":{"rendered":"<p>How did epigenetic research start? Thanks to KP I learned about the biography of Paul Kammerer &#8220;Der Kr\u00f6tenk&uuml;sser&#8221; by <a href=\"http:\/\/www.amazon.de\/Kr\u00f6tenk&uuml;sser-Arthur-Koestler\/dp\/3499168642\">Arthur K\u00f6stler<\/a>. Wikipedia summarizes the rather long (and sad) story<!--more--><\/p>\n<blockquote><p>\nPaul Kammerer (1880-1926) was an Austrian biologist who studied and advocated the discredited Lamarckian theory of inheritance &#8230; Dr. G. K. Noble, Curator of Reptiles at the American Museum of Natural History, &#8230; claimed that the black pads actually had a far more mundane explanation: it had simply been injected there with Indian ink. Six weeks later, Kammerer shot himself in the forest of Schneeberg.\n<\/p><\/blockquote>\n<p>But there are now some more <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19731234?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&#038;ordinalpos=1\">accounts on Kammerer<\/a><\/p>\n<blockquote><p>\nModification of the extracellular matrix of the egg as described by Kammerer provides a plausible cause for altered gene methylation patterns. Traits such as altered egg and adult body size in Kammerer&#8217;s &#8220;treated&#8221; toads are inherited epigenetically in other tetrapods.\n<\/p><\/blockquote>\n<p>When will Kammerer be rehabilitated?<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 17.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>How did epigenetic research start? Thanks to KP I learned about the biography of Paul Kammerer &#8220;Der Kr\u00f6tenk&uuml;sser&#8221; by Arthur K\u00f6stler. Wikipedia summarizes the rather long (and sad) story &nbsp; CC-BY-NC Science Surf , accessed 17.04.2026<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[287],"class_list":["post-2977","post","type-post","status-publish","format-standard","hentry","category-genetics-biology","tag-epigenetics"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2977","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=2977"}],"version-history":[{"count":12,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2977\/revisions"}],"predecessor-version":[{"id":3599,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/2977\/revisions\/3599"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=2977"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=2977"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=2977"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}