{"id":4473,"date":"2010-06-13T10:54:16","date_gmt":"2010-06-13T08:54:16","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=4473"},"modified":"2010-06-19T17:43:00","modified_gmt":"2010-06-19T15:43:00","slug":"multiple-layers-of-heritability-like-a-russian-matryoshka-doll","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2010\/06\/multiple-layers-of-heritability-like-a-russian-matryoshka-doll\/","title":{"rendered":"Multiple layers of heritability like a Russian matryoshka doll"},"content":{"rendered":"<p>Here comes my most favorite paper in 2010 so far, clearly written and elegant in it&#8217;s simplicity. It is printed in this week&#8217; <a href=\"http:\/\/www.nature.com\/nature\/journal\/v465\/n7299\/abs\/nature09230.html\">Nature magazine<\/a><\/p>\n<blockquote><p>\nOne reason for this is that epigenetic factors are sometimes malleable and plastic enough to react to cues from the external and internal environments. Such induced epigenetic changes can be solidified and propagated during cell division, resulting in permanent maintenance of the acquired phenotype. <\/p><\/blockquote>\n<p>Petronis sees heritability as multiple layers (like a Russian matryoshka doll) which is a far more appropriate view than the current DNA sequence based view.<br \/>\nThe paper touches many points that I will also include in a forthcoming review where I am describing epigenetics as a buffering system before changes are permanently written in the genome, yea, yea.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 13.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Here comes my most favorite paper in 2010 so far, clearly written and elegant in it&#8217;s simplicity. It is printed in this week&#8217; Nature magazine One reason for this is that epigenetic factors are sometimes malleable and plastic enough to react to cues from the external and internal environments. Such induced epigenetic changes can be &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2010\/06\/multiple-layers-of-heritability-like-a-russian-matryoshka-doll\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Multiple layers of heritability like a Russian matryoshka doll<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[2650],"class_list":["post-4473","post","type-post","status-publish","format-standard","hentry","category-genetics-biology","tag-complex-disease-genetics"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/4473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=4473"}],"version-history":[{"count":2,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/4473\/revisions"}],"predecessor-version":[{"id":4528,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/4473\/revisions\/4528"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=4473"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=4473"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=4473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}