{"id":61,"date":"2006-08-11T11:51:20","date_gmt":"2006-08-11T09:51:20","guid":{"rendered":"http:\/\/146.107.134.84\/wordpress\/index.php\/2006\/08\/11\/time-bomb-folate-revisited\/"},"modified":"2006-08-11T14:27:46","modified_gmt":"2006-08-11T12:27:46","slug":"time-bomb-folate-revisited","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2006\/08\/time-bomb-folate-revisited\/","title":{"rendered":"Time bomb – revisited"},"content":{"rendered":"

I revisited a 2005 paper on “Folic acid – vitamin and panacea or genetic genetic time bomb<\/a>“. From the abstract: “We live in a health-conscious age \u00e2\u20ac\u201d many of us supplement our diet with essential micronutrients … so-called ‘functional foods’ … We examine this issue in relation to the B-group vitamin folic acid, and ask whether supplementation with this vitamin could introduce a strong genetic selection pressure<\/font>…” As I found this paper highly interesting, here is my analysis, how the story goes on:<\/p>\n

    \n
  1. Martinez-Frias, ML. Folic acid: a public-health challenge. LANCET.<\/li>\n
  2. Kafadar, AM. C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas. ANTICANCER RESEARCH.<\/li>\n
  3. Kelemen, LE. The role of folate receptor alpha in cancer development, progression and treatment: Cause, consequence or innocent bystander?. INTERNATIONAL JOURNAL OF CANCER.<\/li>\n
  4. Nazarenko, MS. Frequencies of C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene at the early stage of human development. RUSSIAN JOURNAL OF GENETICS.<\/li>\n
  5. Ferguson, LR. Nutrigenomics – Integrating genomic approaches into nutrition research. MOLECULAR DIAGNOSIS & THERAPY.<\/li>\n
  6. Soloway, PD. Gene nutrient interactions and evolution. NUTRITION REVIEWS.<\/li>\n
  7. Eichholzer, M.. Folic acid: a public-health challenge. LANCET.<\/li>\n
  8. Houghton, LA. [6S]-5-Methyltetrahydrofolate is at least as effective as folic acid in preventing a decline in blood folate concentrations during lactation. AMERICAN JOURNAL OF CLINICAL NUTRITION.<\/li>\n
  9. Ejarque, I. A bioinformatic approach to epigenetic susceptibility in non-disjunctional diseases. BIOLOGICAL AND MEDICAL DATA ANALYSIS, PROCEEDINGS.<\/li>\n
  10. Sweeney, MR. Evidence of unmetabolised folic acid in cord blood of newborn and serum of 4-day-old infants. BRITISH JOURNAL OF NUTRITION.<\/li>\n
  11. Lucock, MD. The antifolate activity of tea catechins. CANCER RESEARCH.<\/li>\n
  12. Kelemen, LE. Multivitamin and alcohol intake and folate receptor alpha expression in ovarian cancer. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION.<\/li>\n
  13. Allegrucci, C. Human embryonic stem cells as a model for nutritional programming: An evaluation. REPRODUCTIVE TOXICOLOGY.<\/li>\n<\/ol>\n\n

     <\/p>\n

    \n CC-BY-NC Science Surf , accessed 02.05.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"

    I revisited a 2005 paper on “Folic acid – vitamin and panacea or genetic genetic time bomb“. From the abstract: “We live in a health-conscious age \u00e2\u20ac\u201d many of us supplement our diet with essential micronutrients … so-called ‘functional foods’ … We examine this issue in relation to the B-group vitamin folic acid, and ask … Continue reading Time bomb – revisited<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[2945,4],"class_list":["post-61","post","type-post","status-publish","format-standard","hentry","category-genetics-biology","tag-genetics-biology","tag-population-epidemiology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/61","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=61"}],"version-history":[{"count":0,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/61\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=61"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=61"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}