{"id":620,"date":"2007-01-29T16:03:30","date_gmt":"2007-01-29T15:03:30","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/2007\/01\/29\/allergy-and-dc-antigen-processing-vitamin-versus-hygiene-hypothesis\/"},"modified":"2019-06-18T10:48:51","modified_gmt":"2019-06-18T09:48:51","slug":"allergy-and-dc-antigen-processing-vitamin-versus-hygiene-hypothesis","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/01\/allergy-and-dc-antigen-processing-vitamin-versus-hygiene-hypothesis\/","title":{"rendered":"Allergy and DC antigen processing: vitamin versus hygiene hypothesis"},"content":{"rendered":"<p>Last week <a href=\"http:\/\/www.sciencemag.org\/cgi\/content\/full\/315\/5808\/107\">Science<\/a> has an update on differential antigen processing by DCs including a key sentence on <a href=\"https:\/\/www.wjst.de\/blog\/2006\/11\/16\/unripe\/\">immature<\/a> DCs:<\/p>\n<blockquote><p>\nCultured immature DCs capture antigen but only process and present it on MHC II after exposure to inflammatory stimuli or TLR ligation.\n<\/p><\/blockquote>\n<p>Although the authors were not aware of current allergy research, they perfectly summarize how <a href=\"http:\/\/www.blackwell-synergy.com\/doi\/abs\/10.1111\/j.1399-3038.2006.00456.x\">vitamin D<\/a> renders DC immature, while hygiene (<a href=\"http:\/\/www.sciencedirect.com\/science?_ob=ArticleURL&#038;_udi=B6T1B-3W95XGN-C&#038;_user=100078&#038;_coverDate=02%2F06%2F1999&#038;_rdoc=1&#038;_fmt=&#038;_orig=search&#038;_sort=d&#038;view=c&#038;_acct=C000007458&#038;_version=1&#038;_urlVersion=0&#038;_userid=100078&#038;md5=1e95e2c532e4f115325f18062082f4a0\">infections<\/a> or <a href=\"http:\/\/www.clinicalmolecularallergy.com\/content\/3\/1\/7\">LPS farm exposure<\/a> ) may antagonize it.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 22.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Last week Science has an update on differential antigen processing by DCs including a key sentence on immature DCs: Cultured immature DCs capture antigen but only process and present it on MHC II after exposure to inflammatory stimuli or TLR ligation. Although the authors were not aware of current allergy research, they perfectly summarize how &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/01\/allergy-and-dc-antigen-processing-vitamin-versus-hygiene-hypothesis\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Allergy and DC antigen processing: vitamin versus hygiene hypothesis<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[2948,12,1096],"class_list":["post-620","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","tag-asthma-allergy","tag-children-future","tag-farming"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=620"}],"version-history":[{"count":1,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/620\/revisions"}],"predecessor-version":[{"id":12734,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/620\/revisions\/12734"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=620"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=620"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}