{"id":7135,"date":"2014-07-22T13:36:01","date_gmt":"2014-07-22T12:36:01","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=7135"},"modified":"2014-07-22T13:36:01","modified_gmt":"2014-07-22T12:36:01","slug":"a-dual-role-of-ige","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2014\/07\/a-dual-role-of-ige\/","title":{"rendered":"A dual role of IgE"},"content":{"rendered":"<p>While my most recent hypothesis paper on the origins of IgE is still under review, I discovered a new study in <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25017467\">Immunity<\/a> that says in a nut shell<\/p>\n<blockquote><p>\nA growing body of evidence indicates that IgE antibodies and mast cells might serve not only as the effectors of immediate hy-persensitivity in subjects with established sensitivity but also as amplifiers during initial antigen exposure in naive subjects, potentially providing early signals for nascent Th2 cell and anti-body responses.\n<\/p><\/blockquote>\n<p>This fits perfectly to what I am saying , that there seem are self-enforcing &#038; uncontrolled loops of a largely abandoned immune function.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 20.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>While my most recent hypothesis paper on the origins of IgE is still under review, I discovered a new study in Immunity that says in a nut shell A growing body of evidence indicates that IgE antibodies and mast cells might serve not only as the effectors of immediate hy-persensitivity in subjects with established sensitivity &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2014\/07\/a-dual-role-of-ige\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">A dual role of IgE<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[2404,2885],"class_list":["post-7135","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","tag-immune-cell","tag-systems-biology"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/7135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=7135"}],"version-history":[{"count":1,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/7135\/revisions"}],"predecessor-version":[{"id":7136,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/7135\/revisions\/7136"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=7135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=7135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=7135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}