{"id":7918,"date":"2015-11-25T18:41:35","date_gmt":"2015-11-25T17:41:35","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=7918"},"modified":"2019-11-01T07:05:24","modified_gmt":"2019-11-01T07:05:24","slug":"gene-doping-using-crisprcas","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2015\/11\/gene-doping-using-crisprcas\/","title":{"rendered":"Gene Doping using CRISPR\/Cas"},"content":{"rendered":"<p>After some first <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2015\/06\/crisprcas9-gesprochen-krisper-kas-nein\/\">\u00a0experiments<\/a>\u00a0in human embryos, there is a new Chinese paper in\u00a0the <a href=\"http:\/\/jmcb.oxfordjournals.org\/content\/early\/2015\/10\/12\/jmcb.mjv061.extract\">Journal of Molecular Biology<\/a>\u00a0showing\u00a0that also gene doping\u00a0is possible\u00a0in mammals.\u00a0\u00a0<a href=\"http:\/\/abcnews.go.com\/Health\/MedicineCuttingEdge\/story?id=7231487&amp;page=1\">Myostatin deficiency<\/a>\u00a0otherwise leads to some really impressive super strength children while it is now possible to knockout this gene artificially. \u00a0Hopefully the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Doping_at_the_Olympic_Games\">WADA<\/a> will test for myostatin gene activity in Rio 2016!<br \/>\nAddendum 4 Dec15: <a href=\"http:\/\/www8.nationalacademies.org\/onpinews\/newsitem.aspx?RecordID=12032015a\">An\u00a0International Summit Statement\u00a0On Human Gene Editing<\/a> says<\/p>\n<blockquote><p>It would be irresponsible to proceed with any clinical use of germline editing unless and until (i) the relevant safety and efficacy issues have been resolved, based on appropriate understanding and balancing of risks, potential benefits, and alternatives, and (ii) there is broad societal consensus about the appropriateness of the proposed application.<\/p><\/blockquote>\n<p>Both conditions are unlikely to be ever met.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 05.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>After some first \u00a0experiments\u00a0in human embryos, there is a new Chinese paper in\u00a0the Journal of Molecular Biology\u00a0showing\u00a0that also gene doping\u00a0is possible\u00a0in mammals.\u00a0\u00a0Myostatin deficiency\u00a0otherwise leads to some really impressive super strength children while it is now possible to knockout this gene artificially. \u00a0Hopefully the WADA will test for myostatin gene activity in Rio 2016! Addendum 4 &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2015\/11\/gene-doping-using-crisprcas\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Gene Doping using CRISPR\/Cas<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[3079,2967,2966,1595,727,2968,2969],"class_list":["post-7918","post","type-post","status-publish","format-standard","hentry","category-philosophy-of-science","tag-genome-editing","tag-wada","tag-editing","tag-ethics","tag-gene","tag-muscle","tag-strength"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/7918","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=7918"}],"version-history":[{"count":5,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/7918\/revisions"}],"predecessor-version":[{"id":7942,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/7918\/revisions\/7942"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=7918"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=7918"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=7918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}