{"id":8137,"date":"2016-04-13T12:50:07","date_gmt":"2016-04-13T11:50:07","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=8137"},"modified":"2019-12-27T11:49:47","modified_gmt":"2019-12-27T11:49:47","slug":"why-all-allergy-and-vitamin-d-trials-failed-so-far","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2016\/04\/why-all-allergy-and-vitamin-d-trials-failed-so-far\/","title":{"rendered":"Why allergy and vitamin D trials failed so far"},"content":{"rendered":"<p>The following figure highlights the exposure scheme in the\u00a0three published vitamin D \/ allergy clinical trials so far:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27060679\">Grant 2016<\/a>, <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26813209\">Litonjua 2016<\/a> and\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26813208\">Chawes 2016<\/a>.<\/p>\n<p><a href=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2016\/04\/sc.jpg\" data-rel=\"key-image-0\" data-rl_title=\"\" data-rl_caption=\"\" title=\"\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-8138 size-large\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2016\/04\/sc-761x500.jpg\" alt=\"sc\" width=\"761\" height=\"500\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2016\/04\/sc-761x500.jpg 761w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2016\/04\/sc-620x407.jpg 620w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2016\/04\/sc-768x504.jpg 768w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2016\/04\/sc.jpg 1515w\" sizes=\"auto, (max-width: 761px) 100vw, 761px\" \/><\/a><\/p>\n<p>None of them found anything important, maybe due to the\u00a0design flaw in all these studies?<\/p>\n<p>All\u00a0three studies have been designed with the assumption of a beneficial vitamin D effect.<\/p>\n<p>They are dose finding studies that do not allow to prove or disprove any vitamin D effect.<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 10.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>The following figure highlights the exposure scheme in the\u00a0three published vitamin D \/ allergy clinical trials so far:\u00a0Grant 2016, Litonjua 2016 and\u00a0Chawes 2016. None of them found anything important, maybe due to the\u00a0design flaw in all these studies? All\u00a0three studies have been designed with the assumption of a beneficial vitamin D effect. They are dose &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2016\/04\/why-all-allergy-and-vitamin-d-trials-failed-so-far\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Why allergy and vitamin D trials failed so far<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,10],"tags":[],"class_list":["post-8137","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-sunshine-vitamin"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/8137","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=8137"}],"version-history":[{"count":7,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/8137\/revisions"}],"predecessor-version":[{"id":14835,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/8137\/revisions\/14835"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=8137"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=8137"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=8137"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}