{"id":830,"date":"2007-04-01T13:11:41","date_gmt":"2007-04-01T12:11:41","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/2007\/04\/01\/divide-and-conquer\/"},"modified":"2007-04-02T13:21:27","modified_gmt":"2007-04-02T12:21:27","slug":"divide-and-conquer","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2007\/04\/divide-and-conquer\/","title":{"rendered":"Divide and conquer"},"content":{"rendered":"<p>Science has an <a href=\"http:\/\/www.sciencemag.org\/cgi\/content\/abstract\/315\/5819\/1687?maxtoshow=&#038;HITS=10&#038;hits=10&#038;RESULTFORMAT=&#038;fulltext=asymmetry&#038;searchid=1&#038;FIRSTINDEX=0&#038;sortspec=date&#038;resourcetype=HWCIT\">interesting paper<\/a> that relates to an <a href=\"https:\/\/www.wjst.de\/blog\/2007\/01\/12\/a-longe-fuse\/\">earlier post<\/a> here and a central question in immunology. How do T cells differentiate int both short-lived effector cells (that combat infections) and long-lived memory cells.<!--more--><\/p>\n<blockquote><p>\nWe show that a dividing T lymphocyte initially responding to a microbe exhibits unequal partitioning of proteins that mediate signaling, cell fate specification, and asymmetric cell division. Asymmetric segregation of determinants appears to be coordinated by prolonged interaction between the T cell and its antigen-presenting cell before division.\n<\/p><\/blockquote>\n<p>So, at least for <em>Listeria<\/em> antigen, it may look like this<a href='https:\/\/www.wjst.de\/blog\/2007\/04\/01\/divide-and-conquer\/p1000996-1jpg\/' rel='attachment wp-att-829' title='p1000996-1.JPG'><img src='https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2007\/04\/p1000996-1.JPG' alt='p1000996-1.JPG' \/><\/a><\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 09.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Science has an interesting paper that relates to an earlier post here and a central question in immunology. How do T cells differentiate int both short-lived effector cells (that combat infections) and long-lived memory cells. &nbsp; CC-BY-NC Science Surf , accessed 09.04.2026<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[885,891,890,892,889],"class_list":["post-830","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology","tag-t-cells","tag-asymmetry","tag-divide","tag-immune-memory","tag-lymphocytes"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/830","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=830"}],"version-history":[{"count":0,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/830\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=830"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=830"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=830"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}