{"id":8824,"date":"2017-01-09T09:07:57","date_gmt":"2017-01-09T08:07:57","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=8824"},"modified":"2017-01-09T15:21:56","modified_gmt":"2017-01-09T14:21:56","slug":"the-end-of-the-vitamin-d-deficiency-debate-8-facts","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2017\/01\/the-end-of-the-vitamin-d-deficiency-debate-8-facts\/","title":{"rendered":"The end of the vitamin D deficiency debate? 8 facts"},"content":{"rendered":"<p>Most recently, a NEJM paper &#8220;<a href=\"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMp1608005\">Vitamin D Deficiency \u2014 Is There Really a Pandemic?<\/a>&#8221; by Manson, Brannon, Rosen, and Taylor explains the big\u00a0misunderstandings that let some authors conclude that whole populations are being vitamin D deficient. Just to recall, the IOM recommended in 2010 serum concentrations of vitamin D (i.e., 25-hydroxyvitamin D\u00a0[25(OH)D]) above <em>20 ng per milliliter<\/em> (or 50 nmol per liter) as appropriate level and supplementation with <em>600 to 800 IU per day<\/em> as Recommended Dietary Allowance (RDA).\u00a0And here are the 8\u00a0facts:<!--more--><\/p>\n<ol>\n<li>The RDA reflects the estimated requirement for people at the highest end of the distribution. Practically everyone in the population (at least 97.5%, or within 2 SD of the median) will have a requirement below the RDA!<\/li>\n<li>The RDA assume minimal to no sun exposure!<\/li>\n<li>The RDA does NOT provide a \u201ccut point\u201d! It is NOT true that the entire population must have a serum 25(OH)D level above 20 ng per milliliter to achieve good bone health.<\/li>\n<li>According to NHANES data, less than 6% of US Americans are deficient in vitamin D serum levels!<\/li>\n<li>The relationship between serum 25(OH)D and PTH is inconsistent, and no clear threshold defining \u201csufficiency\u201d has been established!<\/li>\n<li>Vitamin D is a hormone of concern, but current levels of deficiency do not constitute a pandemic!<\/li>\n<li>There is also a tolerable Upper Intake Level for vitamin D intake with adverse effects! It has been set by the IOM to 4000 IU daily with a resulting serum 25(OH)D concentration of approximately 50 ng per milliliter (125 nmol per liter).<\/li>\n<li>For otherwise healthy patients (except osteoporosis, osteomalacia, malabsorption, use of anticonvulsants, institutionalization), routine screening is not recommended!<\/li>\n<\/ol>\n<p><!---I was quite pleased to find only now that the IOM 2010 report cited my work on page 168 and 169---><br \/>\nin German: &#8220;<a href=\"https:\/\/www.springermedizin.de\/endokrinologie\/ernaehrung\/vitamin-d-ist-der-hype-bald-vorbei\/10216478?wt_mc=nl.upd.SM_NL_Sonder_Videos2016.Die+meistgeklickten+Videos+2016.L_42.x\">Ist der Hype bald vorbei?<\/a>&#8220;<\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 28.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>Most recently, a NEJM paper &#8220;Vitamin D Deficiency \u2014 Is There Really a Pandemic?&#8221; by Manson, Brannon, Rosen, and Taylor explains the big\u00a0misunderstandings that let some authors conclude that whole populations are being vitamin D deficient. Just to recall, the IOM recommended in 2010 serum concentrations of vitamin D (i.e., 25-hydroxyvitamin D\u00a0[25(OH)D]) above 20 ng &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2017\/01\/the-end-of-the-vitamin-d-deficiency-debate-8-facts\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">The end of the vitamin D deficiency debate? 8 facts<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[2994,2791,2995,2996,2940,1287],"class_list":["post-8824","post","type-post","status-publish","format-standard","hentry","category-sunshine-vitamin","tag-artificial","tag-discussion","tag-hype","tag-misunderstanding","tag-vitamin-d-deficiency","tag-vitamin-d"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/8824","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=8824"}],"version-history":[{"count":7,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/8824\/revisions"}],"predecessor-version":[{"id":8831,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/8824\/revisions\/8831"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=8824"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=8824"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=8824"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}