{"id":9162,"date":"2017-11-21T15:28:03","date_gmt":"2017-11-21T14:28:03","guid":{"rendered":"http:\/\/www.wjst.de\/blog\/?p=9162"},"modified":"2022-02-14T13:45:07","modified_gmt":"2022-02-14T11:45:07","slug":"timeline-asthma-allergy-genetics","status":"publish","type":"post","link":"https:\/\/www.wjst.de\/blog\/sciencesurf\/2017\/11\/timeline-asthma-allergy-genetics\/","title":{"rendered":"Timeline asthma \/ allergy genetics"},"content":{"rendered":"<p>First Genetic Study<br \/>\n1923 AF. Coca.<a href=\"https:\/\/www.jimmunol.org\/content\/8\/3\">J Immunol <b>8<\/b>:163-171<\/a><\/p>\n<p>First Linkage Study (AB0 blood group)<br \/>\n1936. I. Zieve,\u00a0<a href=\"https:\/\/onlinelibrary.wiley.com\/toc\/20501439\/1936\/7\/2\">Ann Hum Gen\u00a0<b>7<\/b>:4074, 163-178<\/a><\/p>\n<p>First Molecular Study (HLA)<br \/>\n1973 D. Marsh,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/4685040\/\">Science <b>179<\/b>:4074, 691-3<\/a><\/p>\n<p>Second Linkage Study (SLC14A1)<br \/>\n1985, H. Eiberg, Cytogenet Cell Genet <strong>40<\/strong>: 622 -journal discontinued, no online archive-<\/p>\n<p>Third Linkage Study (11q31)\u00a0 &#8211; <a href=\"https:\/\/pubpeer.com\/publications\/36DE841F10D2C1891A51969B055528\">questionable results<\/a> &#8211;<br \/>\n1989 W. Cookson,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2566826\/\">Lancet <b>1<\/b>:8650, 1292-5<\/a><\/p>\n<p>First Modern Family Study<br \/>\n1992 S. Dold, \u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1520004\/\">Arch Dis Child <b>67<\/b>:8, 1018-22<\/a><\/p>\n<p>First gene (Fc\u2208RI-\u03b2)<br \/>\n1993 A.J.Sandford,\u00a0 The Lancet \u00a0<b>341<\/b>:8, 332-334<\/p>\n<p>First true gene (IL4)<br \/>\n1994 D. Marsh,\u00a0Science <b>264<\/b>:5162, 1152-6<\/p>\n<p>First Genomewide Linkage Scan<br \/>\n1996 S. Daniels, Nature <b>383<\/b>:6597, 247-50<\/p>\n<p>Transatlantic Airway Conference Key Biscayne FL<br \/>\n1997 N. Zamel (only reported later by Thompson\u00a0 2003 and Duffy 2019)<\/p>\n<p>Second Genomewide Linkage Scan<br \/>\n1997 CSGA \u00a0Nature Genetics\u00a0<b>15<\/b>:389-392<\/p>\n<p>Third Genomewide Linkage Scan<br \/>\n1999 M. Wjst, \u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10333435\/\">Genomics\u00a0<b>58<\/b>:1-8<\/a><\/p>\n<p>First GWAS<br \/>\n2007 M. Moffatt,\u00a0Nat Genet <b>15<\/b>:389-392<\/p>\n<p>Second GWAS<br \/>\n2008 C. Ober, \u00a0NEJM <strong>358<\/strong>: 1682-91<\/p>\n<p><a href=\"https:\/\/www.ebi.ac.uk\/gwas\/search?query=asthma#study\">then it is getting confusing<\/a><\/p>\n<p><a href=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2017\/11\/Bildschirmfoto-2018-03-20-um-12.18.39.jpg\" data-rel=\"key-image-0\" data-rl_title=\"\" data-rl_caption=\"\" title=\"\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-9800\" src=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2017\/11\/Bildschirmfoto-2018-03-20-um-12.18.39-620x593.jpg\" alt=\"\" width=\"620\" height=\"593\" srcset=\"https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2017\/11\/Bildschirmfoto-2018-03-20-um-12.18.39-620x593.jpg 620w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2017\/11\/Bildschirmfoto-2018-03-20-um-12.18.39-768x734.jpg 768w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2017\/11\/Bildschirmfoto-2018-03-20-um-12.18.39-523x500.jpg 523w, https:\/\/www.wjst.de\/blog\/wp-content\/uploads\/2017\/11\/Bildschirmfoto-2018-03-20-um-12.18.39.jpg 1273w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><\/p>\n\n<p>&nbsp;<\/p>\n<div class=\"bottom-note\">\n  <span class=\"mod1\">CC-BY-NC Science Surf , accessed 17.04.2026<\/span>\n <\/div>","protected":false},"excerpt":{"rendered":"<p>First Genetic Study 1923 AF. Coca.J Immunol 8:163-171 First Linkage Study (AB0 blood group) 1936. I. Zieve,\u00a0Ann Hum Gen\u00a07:4074, 163-178 First Molecular Study (HLA) 1973 D. Marsh,\u00a0Science 179:4074, 691-3 Second Linkage Study (SLC14A1) 1985, H. Eiberg, Cytogenet Cell Genet 40: 622 -journal discontinued, no online archive- Third Linkage Study (11q31)\u00a0 &#8211; questionable results &#8211; 1989 &hellip; <a href=\"https:\/\/www.wjst.de\/blog\/sciencesurf\/2017\/11\/timeline-asthma-allergy-genetics\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Timeline asthma \/ allergy genetics<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,2],"tags":[3742],"class_list":["post-9162","post","type-post","status-publish","format-standard","hentry","category-asthma-allergy","category-genetics-biology","tag-key-biscayne"],"_links":{"self":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/9162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/comments?post=9162"}],"version-history":[{"count":11,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/9162\/revisions"}],"predecessor-version":[{"id":19337,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/posts\/9162\/revisions\/19337"}],"wp:attachment":[{"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/media?parent=9162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/categories?post=9162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wjst.de\/blog\/wp-json\/wp\/v2\/tags?post=9162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}