Loss of IL33 -/- protects against allergy

A new paper in Nat Comm shows the power of natural human gene knockouts. Maybe the finding is not really novel but it finally proves the candidate genes Рthe most important asthma/allergy paper in the last 2 years!

IL33, FLG, HLA-DQB1
GSDMB, BTN3A2, CCHCR1

This is even a nice addition to the most recent review of primary atopic disorders although IL33 is only depicted there in Fig 1.