Working in a field where hundreds of papers are published every year and none is ever retracted, I highly appreciate a letter in Science.
…D1 dopamine receptor (D1R)-stimulated intracellular Ca2+ release was attributed to a direct interaction with calcyon … the ability of calcyon and D1Rs to co-immunoprecipitate when co-expressed in cells as reported presumably stems from the association of both proteins with clathrin-coated vesicles…thus, the isolation of the calcyon clone in a Y2H screen with D1Rs appears to have been adventitious…
In my opinion this comment advance science and give the authors a much higher credibility than any further paper. Yea, yea.
Hi Matthias,
Your nice blog about this retraction led me to contact the Schizophrenia Research Forum
http://www.schizophreniaforum.org/new/detail.asp?id=1312
A story about this retraction has recently been posted.
Thanks for this !!
Cheers
John