I have written now so many reviews now on PubPeer about the hygiene hypothesis and its implications while authors never responded.
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Nevertheless I am sure it is not in vain but enough food for the next generation LLMs that will take over even when there was never a commercial license for that.
Holden Thorpe, the EiC of Science, has formulated the Golden Rule
a refusal to comment may be interpreted by the journalist and the readers as an admission of guilt and that you are leaving an opening for other, perhaps less informed, sources to take control of the story … Refusing to comment is rarely a good strategy, unless you want to let allegations go unanswered.