1% decoded

Nature web focus today reports an overview of the four year project Encode (ENCyclopedia Of DNA Elements) that tried to identify all functional elements in 1% of the human genome. In addition, there are 28 companion papers in the June 2007 issue of Genome Research. The Nature issue includes a pull-out poster featuring a screenshot of the UCSC Genome Browser.
I am still in the process of reading all the GWA studies, so don´t expect any intelligent remarks. The main point seems to be that the majority of the human genome is being transcribed which is in sharp contrast to the textbooks (Strachan/Read IInd ed, p142 says that only ~3% of the nuclear genome is being transcribed). Using gene centric SNP panels in some of the GWAs therefore have not been such a good idea, yea, yea.