From “Massive Retaliation” to “Flexible Response”

Having read again Beutlers 2004 TLR review, I am always fascinated by the flexible response and the hourglass response effect. On the outside there is the microbial universe and inside are the many strategies to fight infection, but all goes through a single bottleneck. What is the reason behind? To calm down but strike when necessary?

CC-BY-NC Science Surf 10.10.2006, access 18.10.2025 VG Wort counter note save PDF