Schlagwort-Archive: epigenetic regulation

Is there any environmental conditioning of vitamin D metabolism?

So far, I haven’t seen so much work about epigenetic regulation of vitamin D. There was already a paper in 2005 that showed how treatment with the

methylation inhibitor 5-aza-2′-deoxycytidine together with the deacetylation inhibitor trichostatin A resulted in elevation of both CYP27B1 and CYP24 mRNA expression demonstrating that even in normal human prostate cells expression of Vitamin D hydroxylases may be under epigenetic control

Is there any environmental conditioning of vitamin D metabolism? weiterlesen