It was difficult to find but I knew it should be there: a letter of Herrmann von Helmholtz about his attempts to cure hay fever. Published secondhand in Nature May 14, 1874, von Helmholtz describes the vibrio like bodies in his own nasal fluid and the successful local treatment with quinine. There is a consecutive letter that did not confirm this effect.
I do not know how this treatment could have worked. Is it fiction, placebo or any true antiparasitic side-effect? On the other hand, we know of quinine induced allergy. Case observations remain doubtful!
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