Finally, linkage and association data can be used together after downloading new software using genotype inference.
It reduces the number of genotyping reactions and increases the power of genome-wide association studies. Our method combines sparse marker data from a linkage scan and high-resolution SNP genotypes for several individuals to infer genotypes for related individuals.
- could already test association only in linked families
- knew that linkage genome scans> will improve the power of association
- could evaluate by stepc if a polymorphisms explains a linkage result
but this seems to be the best recycling for our old fashioned linkage data. Yea, yea.