Here are the most recent GWAS data for asthma. Peaks are not identical peaks but quite similar.
How it is going in 2021 …
And here is how it started 1986
So, more than 2 decades ago we found hits on chromosome 2, 6, 9, 12 (missing chr17q21 where our marker coverage wasn’t probably good enough). It seems that this was the first identification of the IL33 region although IL33 was described only 7 years later. Remarkably, this result was possible with just 415 individuals instead of 500,000 individuals nowadays (see also the asthma genetics timeline).