Are there any news in the allergy & vitamin D controversy?
SPQR (is not necessary to be remembered) but certainly TSLP – at least if you are interested in allergy research (see the discussion here 2 years ago) when we knew from a PNAS paper that topical vitamin D3 induces thymic stromal lymphopoietin and triggers atopic dermatitis (in mice). Now there is an update – TSLP even mediates the progression to experimental asthma
vitamin D3 … not only triggers AD as we previously reported but also aggravates experimental allergic asthma induced by ovalbumin sensitization and challenge. Our study, which provides a mouse model to study human “atopic march
will be continued after Continue reading T_S_L_P
As always, a longer literature search prevents from new discoveries… Here comes a nice piece from 1952 on the antagonistic effect of LPS on vitamin D (Is that really LPS or did I interpret it wrong?). Although not included in my recent review on vitamin D and allergy – I attributed the effect to Lyakh et al. – here is the first description of this effect. Continue reading A factor in hay prevents vitamin D action