Two days ago I heard an interesting by Andreas Beyer about using wiring diagrams as a bioinformatics tool box for simulating complex biological relationships. This is something that can be found also in this recent nat gen review but even more detailed in new work on eQTLs. So far, however, there is not proof that any of these methods behave much better than others in the absence of a gold standard in bioinformatics, yea, yea.
Here is what worked for me: Start up MS SQL server and run a tool that can be compiled from sources at Codeproject. Transfer the resulting SQLITE3 database to the Mac where it can be accessed by R via the RSQLite library. Many thanks to Liron Levi and his patient help with tables having more than 1000 columns!
I am in the process of setting up a graphical ER management tool while the native ODBC driver still seem to have some problems. Any workaround is greatly appreciated.
Adorno in Minima Moralia: “Es gibt kein richtiges Leben im Falschen” (No true life in the wrong one).
or any patent from oblivion, in preservations below the moon – the predicament of Sir Thomas Browne in Cyril Connolly’s “Enemies of Promise”, a book just recently recommended to me. My pidgin science is certainly not good enough to appreciate enough to wonderful descriptions like on page 30 “look on my works ye mortals and despair”. The scientist Continue reading In vain do individuals hope for immortality
… also for some people in the field the main paradigma in science. To cite Wikipedia
Bush’s assertion — and the sign itself — became controversial after guerilla warfare in Iraq increased during the Iraqi insurgency. The vast majority of casualties, among both coalition (approximately 98.3% as of October 2008) and Iraqi combatants, and among Iraqi civilians, have occurred after the speech. Due to this fact, “Mission Accomplished” is now a winged word for uncompleted operations with an unclear ending.
goodbye GB!
Another one of my favorites, this morning on BR2 when driving to Gauting, entrainment Continue reading Entrainment
Together with some friends we attended the famous Kandinsky exhibition here at the Lenbachhaus in Munich. Continue reading Le bleu des ciels
Found at Donaueschinger Musiktage: The Necks! Continue reading Some Australian music
I am quoting from a PLoS one press release of brain’s ‘Hate Circuit’ identified:
People who view pictures of someone they hate display activity in distinct areas of the brain that, together, may be thought of as a ‘hate circuit’, according to new research by scientists at UCL (University College London). Continue reading People know their assassins
Blood has now also an account on the vitamin hypothesis.
Following some earlier descriptions in Reed 1932, Selye 1962, Wjst 1999 and Wieringa 2008, the discovery frequency seems to increase – a good sign for some progress. Bischoff writes about vitamin A where we have only some limited evidence.
Here is the abstract of another pro D3 article by Gilchrest in the AJCN with a few comments by me (notJuan Carlos) Continue reading Porque no te callas?
Just recently I came across a site (but can’t rememeber the URL) – basically saying that this is not a blog but just a few notes, how and why I did something to convince me at a later time of its justification. Yea, yea.
I had already a thread here about asthma and iatrogenic factors last month including estrogens, vaccines, antibiotics, vitamin D, paracetamol, and Caesarean section. There may be even another kid on the block: folate. At least in mice in utero supplementation with methyl donors enhances allergic airway disease Continue reading Asthma: a iatrogenic disease cont’d
Local newspapers just report a suicide – where the corpse had to be identified in the forensic department. Skin cells turned out to be male, blood cells to be female. The solution to this paradox was quite simple Continue reading A man with a female DNA
We already discussed here “how doctors think?k” while a new essay in the Lancet now even asks “Can doctors think“?
Disease can be recognised by the doctor and the patient (mumps), by the doctor but not the patient (schizophrenia), by some doctors but not others (social phobia), by doctors in some times but not others (melancholy …), and by doctors in some places but not others (embedded incisor tooth because an ancestor’s ghost is angry).
marvelous, yea, yea.
