All posts by admin

Philosophy, Theology

Precisez, mon cher, precisez

I am currently reading Geert Mak’s “In Europa”, an excellent history of European history (in particular important for me as my high school education ended with the Weimar republic! I always wanted to ask my former teacher R. Grundel for the reasons but he died recently). This book finds and connects all the lost threads while being excellently written and easy to read. I am citing here from the notes of Harold Nicolson (p 137), a young British diplomat, who served as an advisor to Lloyd George, Clémenceau and Wilson: Continue reading Precisez, mon cher, precisez →

 

CC-BY-NC Science Surf accessed 10.11.2025
Genetics, Philosophy

Who’s the boss?

A news focus in Science Magazine asks “Who’s the queen? Ask the genes” and shows new research that in some social insects nature, not nurture, determines whether offspring becomes worker or royalty.
I am not aware of any genetic studies of bosses but there might be also inherited personality traits in humans that favor a certain behavior.
Given my interest in a German gene-test law and the corresponding passivity of the German government, I am now proposing a “Biobank German Bundestag” that will allow me to go for gene variants that make our representatives different from us, the commonalty. I am sure that we will have a gene test law within 12 months …

 

CC-BY-NC Science Surf accessed 10.11.2025
Genetics, Vitamins

You may fool all the people some of the time

Nature news reports an unpublished meta analysis of Cesarean section and asthma risk. The authors interpret the outcome in the light of the hygiene hypothesis: unhygienic siblings, risky! Normal delivery, risky!! No early bullshit, risky!!!
Again, delivery mode may be a proxy for physician contact and iatrogenic causes. Having heard today also lectures that take the hygiene hypothesis for granted, the old adage comes to my mind:

You may fool all the people some of the time. You can even fool some of the people all of the time. But you cannot fool all of the people all the time.

 

CC-BY-NC Science Surf accessed 10.11.2025
Genetics

Origin of toll like

I always thought that toll like receptors owe their name to the toll function of the immune system. As I learned only today, the origin is with the German “toll” (amazing, phantastic) ascribed by Christiane Nüsslein-Volhard to a Drosophila protein.

 

CC-BY-NC Science Surf accessed 10.11.2025
Allergy, Genetics, Software

GPS for biological pathways

After running a dual core CPU for two weeks I have a list here of all transcripts that are associated with the “ORMDL3” SNP gene cluster. Making sense from this list is a difficult task even with dozen of dedicated websites.
To get an overview of what is available I would start Continue reading GPS for biological pathways →

 

CC-BY-NC Science Surf accessed 10.11.2025
Allergy

Eat peanut to avoid peanut allergy

There is a new comment in the BMJ about a Lords committee report

a number of recent epidemiological studies had indicated that early peanut consumption in countries such as Israel was associated with a low incidence of peanut allergy in the population. These observations had led many academics to say that exposing a child’s immune system to peanut allergen at an early age might result in tolerance.

It seems that allergen avoidance versus sportively exposure is a never ending story – forth and back and back and forth – and largely irrelevant as being only about the second line of defense?

 

CC-BY-NC Science Surf accessed 10.11.2025
Joke, Philosophy

Look here

From an email that I received today:

while open access has provided the scientific community with broader accessibility, little seems to have been done to make better use of the on-line content. We are trying to address this shortcoming through pubcasts. Pubcasts are 5-10 minute video clips which are integrated with the contents of the open access paper.

I agree with the observation that Open Access hasn´t been very innovative so far in technical terms. On the other hand I feel that my job is less about marketing than development. Are you climbing on this bandwagon? Continue reading Look here →

 

CC-BY-NC Science Surf accessed 10.11.2025
Allergy, Vitamins

Archie Cochrane speaking

I did not expect what a new Cochrane writes on the prevention of nutritional rickets in term born children — Cochrane Database Syst Rev. 2007 concludes

There a only few studies on the prevention of nutritional rickets in term born children. Until new data become available, it appears sound to offer preventive measures (vitamin D or calcium) to groups of high risk, like infants and toddlers; children living in Africa, Asia or the Middle East or migrated children from these regions into areas where rickets is not frequent. Due to a marked clinical heterogeneity and the scarcity of data, the main and adverse effects of preventive measures against nutritional rickets should be investigated in different countries, different age groups and in children of different ethnic origin.

May I summarize: 1. only a few studies; 2. vitamin D OR calcium and 3. to high risk kids only. This looks different to what Nestlé manufactures at the moment.

 

CC-BY-NC Science Surf accessed 10.11.2025