Category Archives: Vitamins

Ig Nobel Prize 2010

I haven’t seen the ceremony award 2010 so far but read of a prize for discovering that symptoms of asthma can be treated with a roller-coaster ride (Simon Rietveld of the University of Amsterdam, The Netherlands, and Ilja van Beest of Tilburg University, The Netherlands) and of the management prize for demonstrating mathematically that organizations would become more efficient if they promoted people at random (Alessandro Pluchino, Andrea Rapisarda, and Cesare Garofalo of the University of Catania, Italy), yea, yea.

 

CC-BY-NC Science Surf 1.10.2010, access 18.10.2025

Once more: Calcium and IgE

Here comes the most striking connection between calcium and IgE that updates some earlier posts here

The fact that the regulation of intracellular Ca2+ concentration is different in various T-cell effectors may offer the opportunity to target key intermediates … to inhibit specifically the functions of one given T-cell subset. Continue reading Once more: Calcium and IgE

 

CC-BY-NC Science Surf 18.06.2010, access 18.10.2025

Hallelujah

Two new exciting papers about Jewish ancestry in the AJHG and Nature probably missed some of the background. As another blogger noted

It is remarkable that Jews have maintained a tangible cultural identity through those 26 centuries of dispersion, and perhaps even more remarkable that genetic studies now show they have maintained a substantial genetic identity as well.

Here is the answer – sharing faith and music. Continue reading Hallelujah

 

CC-BY-NC Science Surf 12.06.2010, access 18.10.2025

Why FFQs don’t predict vitamin D status

Two recent studies used food frequency questionnaires to predict vitamin D status and later allergy (Devereux 2007 and Camargo 2007) probably the only two studies that seem to contradict the vitamin D hypothesis.
New research now reported at the ATS congress [Poster Board # A84] “Measurement of Vitamin D Levels Utilizing Laboratory and Dietary Recall Information from the Tennessee Children’s Respiratory Initiative” and published in Am J Respir Crit Care Med 181;2010:A1890 shows that FFQs don’t predict vitamin D status Continue reading Why FFQs don’t predict vitamin D status

 

CC-BY-NC Science Surf 26.05.2010, access 18.10.2025

When will they ever learn?

A new abstract shows

Perinatal data for singleton children who were prescribed anti-asthmatic medication (n = 61 256) were compared with corresponding data for all singleton children born in Sweden … (n = 1 338 319). … Being the first-born child, maternal age above 44 yr, involuntary childlessness for more than 1 yr, maternal smoking during pregnancy, maternal diabetes mellitus of any kind, pre-eclampsia, caesarean section, and instrumental vaginal delivery were all associated with an increased prescription of anti-asthmatic medication during childhood. Continue reading When will they ever learn?

 

CC-BY-NC Science Surf 10.05.2010, access 18.10.2025

rs4711, uh rs7041

The first GWAS of human vitamin serum D level finds the most important SNPs:

In a genome-wide association study (GWAS) of 4,501 persons of European ancestry drawn from five cohorts, we identified single nucleotide polymorphisms (SNPs) in the gene encoding group-specific component (vitamin D binding) protein, GC, on chromosome 4q12-13 that were associated with 25(OH)D concentrations: rs2282679 (P=2.0 x 10–30), in LD with rs7041, a nonsynonymous SNP (D432E; P=4.1 x 10-22), and rs1155563 (P = 3.8 x 10–25).

Funny, rs7041 is the same variant Continue reading rs4711, uh rs7041

 

CC-BY-NC Science Surf 28.04.2010, access 18.10.2025