It is no secret – there are way too many meta-analyses while original research is missing [blog, paper, paper, paper, paper, journal, journal). Books are about the method are also abundant. Sure, armchair research can be done without getting dirty.
Narrative reviews are much less appreciated nowadays although most of the current “systematic reviews” are basically useless as they are frequently written by “new kids on the block” and not by experienced scientists.
If the current pace continues, we will soon have more reviews than original studies… As another author put it forward it is a “bloated mushroom of evidence”.
The new Lancet has a paper from our own group as well as another one from ISAAC. We have already suggested earlier that asthma is a iatrogenic disease- the ISAAC paper now confirms at least the long suspected association with paracetamol use – gratulations to my London friend who had been working so long on this hypothesis. The accompanying editorial puts in into context:
Furthermore, although many important potential confounders were included in multivariate analyses, confounding by underlying respiratory disease, differences in hygiene, and use of other antipyretics might also explain the findings.
To put it more on a general level – more iatrogenic factors cannot be excluded, yea, yea.
I wonder about the title of a new nature medicine editorial
Breathing easier with breast milk
It is not so much the unwanted analogy to aspiration; the paper simply hasnÂ´t to do anything with breathing. It is a poor narrative of a concomittant NM article repeating many of its prejudices. Although the authors would like to let you belief that they have discovered allergen transfer into breast milk, this is known Continue reading Parascience in nature medicine?
Micro- and macroclimate factors certainly have more influence on our health than being reflected by current research. A new PLOS study now finds that
facilities built more than 50 years ago, characterised by large windows and high ceilings, had greater ventilation than modern naturally ventilated rooms (40 versus 17 air changes per hour) … Old-fashioned clinical areas with high ceilings and large windows provide greatest protection. Natural ventilation costs little and is maintenance free.