What is similiar to SQL injection (in webforms) and retrovirus infection (of mammals)? I think there is always a vulnerable situation (tainted variable by unexpected data entry – or double strand break and ligation) that allows foreign code to be inserted. What is different? Retrovirus insertion is probably position specific while SQL injection can even determine its own target. Yea, yea.
-moblog– Eran Segal et al. describe in Nature a genomic code for correct nucleosome attachment of genomic DNA. DNA must be positioned for access to functional sites of gene activity where 147 bases are wrapped around each nucleosome core. AT is favored where phosphodiesterase backbones face inward and GC where it faces outward. Distance between nucleosomes may be variable – as the accompanying editoral by Timothy Richmond explains (the enigmatic histone H1 question). Do genomes use nucleosome DNA preference to target transcription factor towards appropriate sites? This might expain why current transcription factor models are rather poor as they are using only sequence binding matrices. It reminds me to steganograpy, algorithmic procedures that can be used to hide secret messages in in pictures without affecting the visual impression. Yea, yea.
I am using a HP6515 GPS phone with a Spectec mini SD card and a SD 512K memory card running PPC2003 (which replaced my the older PALMs). I am manging the device with Total Commander (free) and the build-in IPAQ Backup (free); the Today screen uses PocketBreeze (€) and Ilauncher (€). I am navigating with OziExplorer (€), TomTom (€) and Metro (free). For internet access I am using the buildin messaging client, Opera (€) and pRSSreader (free) which works all together without major problems with >21 MB internal memory left. The mp3 mediaplayer (free) is being a good choice. So – display is not so sharp, ear phones have low quality, torch not very light, GPS not as good as standalone devices, WLAN has weak signal, camera a poor quality with a device rather large for a mobile – but there is only 1 device and 1 charger which outweights everything! Yea, yea.
PNAS has an interesting paper: Until now I had believed that the major search engines provide some kind of self-enforcing loops as they show web sites first that are already highly visited. Visitors of these prime websites will then know (and link) only these websites giving them even a higher rank (rich-get-richer). But that does not see to be true. Nay, Nay. The use of search engines actually had an egalitarian effect as shown by empirical and theoretical arguments. On the other hand I can not renember an own paper, that would have received more than 50 citations without being in an “upper-class” journal. Did you ever want ot know how Google works? Check Ghemawat S GH, Leung S-T: The Google file system. ACM, SOSP’03, October 19-22,2003, Bolton Landing, New York.
An anonymous reader at slashdot writes that AOL released search logs of 657,427 users “AOL has released very private data about its users without their permission. While the AOL username has been changed to a random ID number, the ability to analyze all searches by a single user will often lead people to easily determine who the user is, and what they are up to. The data includes personal names, addresses, social security numbers and everything else someone might type into a search box.” The German Green Party already filed a legislation proposal that companies and institutions will need to inform their clients about such accidents. This seems to be very important also for genetic data. Yea, yea.
Slashdot Accommodate Students writes “The BBC is amongst those reporting that the World Wide Web has turned fifteen. However, 6 August 1991 is not the only date claimed as the ‘birthday of the intern.” There is nothing to compare with that scientific evolution. Did Herrmann Hesse think of the internet when writing his “Glasperlenspiel”? Yea, yea.
PLoS ONE may revolutionize science communication. Have a first look at www.plosone.org. As they write: “Be one of the first to appear in this new Open Access 2.0 online forumâ€”and qualify for a great low pre-launch price. We’ll peer review your work and publish it online as soon as possible so that it can start a conversation within the community that will enhance scientific progress.” Will it still be traditional, 1:1 translated publishing system? Or can we even edit any text? What about lists of open questions? And a true synopsis – like the one theologians use to compare the four canonical gospels? Yea, yea.