…a few categories – insertions with and without corresponding fragment or deletions if seen from the second genome (has somebody ever thought about a minimal human genome?), mismatches and inversions….
Lets start a further workup of the evolutionary thread. With the complete human and chimp genome on our harddisks we are now able to compare genome sequence and genome activity…
A welcome initative of the Golden Path Genome Browser: Users often send us notes and hints about how we might better curate and annotate the genome. These contributions are valuable…
…2016! Addendum 4 Dec15: An International Summit Statement On Human Gene Editing says It would be irresponsible to proceed with any clinical use of germline editing unless and until (i)…
…In addition, there are 28 companion papers in the June 2007 issue of Genome Research. The Nature issue includes a pull-out poster featuring a screenshot of the UCSC Genome Browser….
…personal genome service provider. The main question is, what do these data really mean for us? Should we start an Open Source Project Genome Explained to collect the necessary annotation…
…of haplotype-resolved structural variation in human genomes” The incomplete identification of structural variants (SVs) from whole-genome sequencing data limits studies of human genetic diversity and disease association. Here, we apply…
I truly liked the recent Sjoblom study while a new Science letter now raises heavy criticism: … put into stark reality the challenges facing the Human Cancer Genome Project (HCGP)….
…that overall recombination hotspot usage is similar in males and females, with individual hotspots often active in both sexes. Across the genome, roughly 60% of crossovers occurred in hotspots inferred…
Laborjournal 4/2008 reports a new software tool for DNA addicted people: the Personal Genome Explorer which is based on SNP annotation by SNPedia. So, what I tried to institutionalize on…
…the UCSC Genome Browser system, called GAD View, in their new section on Phenotype and Disease Associations. This GAD track allows viewing of disease based genetic association information in the…
Here are some instructions how to create genome coordinate plots with Sigmaplot. The Systat Sigmaplot FAQ recommends for this kind of figures “floating bars” that can be created using two…
Being a former curator for a genetic disease database, I received a PM that explained why the foundation of the Human Genome Variation Society did not include most of the…
courtesy of Craig Venter – whom else? It is also one half of the genome of his only son (the individual denoted 3.5 in Figure 1 of the PLoS paper)….
The idea might not be new – we already diluted DNA already a decade ago ( see this 2003 paper ). A new Nature paper by Peters ( Accurate whole-genome…