Tag Archives: integrity

Systemic science flaw

Bruce Alberts, one of the most reputable living scientist, already back in a 2014 PNAS paper

The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession—and making it difficult for seasoned investigators to produce their best work…

The great majority of biomedical research is conducted by aspiring trainees: by graduate students and postdoctoral fellows. As a result, most successful biomedical scientists train far more scientists than are needed to replace him- or herself…

Competition in pursuit of experimental objectives has always been a part of the scientific enterprise, and it can have positive effects. However, hypercompetition for the resources and positions that are required to conduct science suppresses the creativity, cooperation, risk-taking, and original thinking required to make fundamental discoveries…

The inflated value given to publishing in a small number of so-called “high impact” journals has put pressure on authors to rush into print, cut corners, exaggerate their findings, and overstate the significance of their work.

there is nothing to add.

Integrity of scientific research

I have a new book on my desk that covers most aspects of the recent discussion around research integrity in 60 chapters arranged in 14 sections.


It is a comprehensive overview of research integrity across disciplines. Maybe some chapters are not written by the leading experts in the field. And maybe the scope is super-broad with several off topic chapters like corruption in healthcare. This comes at the cost that other chapters like image integrity are missing. Nevertheless it is the largest body of text so far.


Deep fake image fraud

Doing now another image integrity study, I fear that we may already have the deep fake images in current scientific papers. Never spotted any in the wild which doesn’t mean that it does not exist…

Here are some T cells that I produced this morning.


Continue reading Deep fake image fraud

The Lancet and scientific integrity

We have learned in the past that the Lancet published editorials that clearly separated the journal from the publisher Elsevier

Reed Elsevier’s response is that the sale of military equipment is legal, government supported, and tightly regulated. However, The Lancet‘s collaborations in child survival and health-systems strengthening, for example, risk being tainted by Reed Elsevier’s promotion of the “selling process” of arms.

Of course you can’t sell weapons and distance yourself from selling weapons at the same time…

Good scientists doing wrong

There is an interesting study “When Good People Break Bad: Moral Impression Violations in Everyday Life” by  the Canadian PhD student  Kate Guan and her advisor Steven Heine. It is a phenomenon that is annoying many people if we look at the reactions to Twitter posts und PubPeer entries accusing scientists of wrong doing. The paper provides some explanations Continue reading Good scientists doing wrong

It’s all too much

Charles Day in Physics Today (which is already my view in biomedicine 5 years ago)

Their main conclusion is sobering: As the number of papers in a field increases, researchers find it harder to recognize innovative work. Progress seems to be slowing.

How to buy papers

It is incredible – but probably some kind of advanced fee scam only.

https://twitter.com/ronepz/status/1480035059046313991 Screenshot 10.1.2022 while I can’ t verify the original Facebook post


500€ would be clear bargain compared to the 9500€ that you have to pay here

https://www.nature.com/articles/d41586-020-03324-y Screenshot 10.1.2022

although there is a surplus of 6000€ for the science writer at fiverr and another 50,000€ lab funding to one of the numerous “science charities”  and “patient alliances”.

More content is great. But, how much of that discovery turns out to be unreliable?

A great paper by Josie Fenske

More content is great. But, how much of that discovery turns out to be unreliable?
“The number was 2700 in 2020, but we have 3000 retractions a year now,” says Oransky. The steady increase of retractions from year to year is a pattern that can be observed back to the beginning of Retraction Watch, and there’s no indication of slowing down.


Papers are not sacred – this what I have been advocating even after having personal distress after commenting on a PLoS ONE paper. Nevertheless, the new Nature editorial supports my view

What is needed, instead, is a system of publication that is more meritocratic in its evaluation of performance and productivity in the sciences. It should expand the record of a scientific study past an individual paper, including additional material such as worthy blog posts about the results, media coverage and the number of times that the paper has been downloaded.

where Crossmark may jump in Continue reading Crossmarks