Der chinesische Menschenversuch

Dienstag, 11.12.2018

Was so alles noch möglich ist.

Stanford Center

Scenarios illustrating governance gaps in in the report include: – A reckless CRISPR user who develops and markets a probiotic created with genome editing that has serious unanticipated effects for consumers; – An agricultural biotechnology firm conducting dual use genome editing research that lies outside current oversight, but nonetheless could have negative consequences for human health – An intentional release of a gene drive organism from a lab, that while having limited physical harm, feeds a state-based misinformation campaign with large economic impacts – An accidental release of a gene drive organism due to lack of awareness and uncertainty about the risk classifications and protocols for handling new technologies – A terrorist group using commercial firms that lack strong customer and order screening to use genome editing to weaponize a nonpathogenic bacteria – A state-sponsored program to develop biological weapons for new strategic uses, including covert assassination, using largely publicly available research

Stat hat ein abgelehntes Paper von He ausfindig gemacht

ISPR babies” scientist He Jiankui tried to publish a paper describing additional experiments that made heritable changes in the DNA of human embryos, much like those that led to the birth of the world’s first genome-edited humans. But the paper was rejected by an international journal after outside scientists raised concerns about both its ethics and its scientific validity, STAT has learned. Targeted PCSK9 genome editing in embryos by CRISPR-Cas9 system One Sentence Summary: The efficacy and safety of our in vitro and in vivo studies presented here suggest that targeted PCSK9 genome editing in embryos by CRISPR-Cas9 system provides a potential strategy for the prevention and treatment of familial hypercholesterolemia and coronary heart disease. Feifei Cheng1, Kaijing Chen1, Xiaoqing Zhou1, Shuo Song1, Jinzhou Qin2, Yangran Chen1, Rui Chen1, Dikai Zhang3, Chenglu Qin4, Chenyang Si5, Zhijian Wang6, Dayong Hao7, Renli Zhang8, Michael W. Deem9,10,11, Jiankui He1,* 1 Department of Biology, South University of Science and Technology of China, Shenzhen 518055, China. 2 Department of Human Reproductive Medicine Center, Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, China. 3 Department of Gynecology, Department of Human Reproductive Medicine Center Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, China. 4 Department of Obstetrics, Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, China. 5 Yunnan Key Laboratory of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, China. 6 Department of Cardiovasology, Peking University Shenzhen Hospital, Shenzhen 518036, China.

Das NIH will zwar Forschung einschränken

HIV research halted after NIH freezes acquisition of fetal tissue. Researchers at the National Institutes of Health have been ordered not to acquire new fetal tissue for their research since September, according to Science — the same month the Trump administration began an audit of research using the tissue funded by the NIH and other agencies. The NIH confirmed the suspension on Friday to Science, which reported it affected two NIH labs, including halting an HIV research project.

aber Wired weiss schon wie es weiter gehen wird

Last week, Harvard researchers announced that they plan to edit the DNA of human sperm to see if it’s possible to create IVF babies with lower risks of developing Alzheimer’s later in life.

Ein philosophischer Einwurf

Science with a small “s” is a human enterprise as old as humanity itself. Nibbling on that tasty-looking mushroom and waiting a few hours to see if you get sick? That’s hypothesis testing. Try it a few more times with successively bigger bites, maybe add a bit of open-fire cooking; you’ve got a scientific method going. He’s human experiment is clearly science in this sense. Whether it will become Science with a big “S” remains to be seen. This more rigorous meaning of Science—which seeks to accrue knowledge by progressively, and systematically, reducing uncertainty—has only been around a few hundred years. Its arrival was marked by the development of the scientific paper, published in the pages of peer-reviewed journals.

Die neuen Nobelpreisträger beschwichtigen im Guardian

Winners of this year’s Nobel prize for chemistry say overblown fears about genetically modified foods risk preventing society benefiting from the technology. Prof Frances Arnold, from the US, and Sir Gregory Winter, from Britain, made the comments on Friday ahead of Monday’s presentation of the prize.

Designerbabies wird es angeblich nie geben laut The Conversation

I study the prediction of complex diseases and human traits that result from interactions between multiple genes and lifestyle factors. This research shows that geneticists cannot read the genetic code and know who will be above average in intelligence and athleticism. Such traits and diseases that result from multiple genes and lifestyle factors cannot be predicted using just DNA, and cannot be designed. Not now. And very unlikely ever.

Die Entstehung der (natürlichen) Delta32 Mutation ist immer noch nicht klar

Scientists hypothesize that the mutation gave some sort of advantage to people against the epidemic. This gave these individuals an increased chance of survival and ability to reproduce and pass on the affected allele. Evidence dating the mutation back 700 years ago coincides perfectly with the Black Death. According to this idea, the Black Death drove natural selection in the human population.