Der chinesische Menschenversuch

Donnerstag, 24.1.2019

So geht es auch heute weiter: Die chinesischen Affenversuche sind vom ethischen Standpunkt nicht minder problematisch

The first cohort of five gene-edited monkey clones made from fibroblasts of a monkey with disease phenotypes were born recently at the Institute of Neuroscience (ION) of Chinese Academy of Sciences (CAS) in Shanghai. The expression of BMAL1, a core circadian regulatory transcription factor, was knockout in the donor monkey using CRISPR/Cas9-mediated gene editing at the embryo stage, and the fibroblasts of the donor monkey were used to clone five monkeys using the method of somatic cell nuclear transfer, the same method that generated Zhong Zhong and Hua Hua, the first two cloned monkeys, last year. This major advance, reported on-line in two articles in the journal National Science Review on January 24, demonstrates that a population of customized gene-edited macaque monkeys with uniform genetic background will soon be available for biomedical research.

Ob da die aktuellen Regulationsversuche nicht zu spät kommen?

But most agree major health and science institutions should act quickly. The World Health Organization is assembling a panel to develop global standards for governments to follow. Leaders of the National Academy of Medicine and the National Academy of Sciences in the United States, along with the Chinese Academy of Sciences, have jointly proposed a commission with academies in other countries to develop criteria so scientists can’t “seek out convenient locales for conducting dangerous and unethical experimentation.” The proposal included establishing “an international mechanism that would enable scientists to raise concerns.” The World Economic Forum in Davos has scheduled a discussion of the issue on Thursday.

Savulescu hat es als russisches Genetik Roulette bezeichnet.